Prophylactic antibiotics in gynecologic and obstetric surgery

Research output: Contribution to journalArticle

100 Citations (Scopus)

Abstract

Preventing infections at operative sites has long been a goal of gynecologic and obstetric surgeons. These infections constitute the leading cause of morbidity after both elective and emergent surgical procedures. Serious sequelae such as bacteremia, septic shock, phlegmon, pelvic abscess, septic pelvic thrombophlebitis, wound abscess, and fascial dehiscence may complicate primary infections, with devastating results. Early attempts to prevent postoperative infections concentrated on aseptic techniques and the modification of surgical skills. Soon after the introduction of antibiotics into clinical medicine, surgeons began to administer these drugs to clinically uninfected women to prevent operative-site infection; that practice has been documented and assessed in a large volume of literature. This article reviews the chronologic development of prospective data in the areas of benign gynecology, obstetrics, gynecologic oncology, and infertility and makes recommendations regarding antibiotic prophylaxis of infections associated with surgical procedures.

Original languageEnglish (US)
JournalReviews of Infectious Diseases
Volume13
Issue numberSUPPL. 10
StatePublished - 1991

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Obstetric Surgical Procedures
Gynecologic Surgical Procedures
Anti-Bacterial Agents
Infection
Abscess
Obstetrics
Elective Surgical Procedures
Thrombophlebitis
Cellulitis
Antibiotic Prophylaxis
Clinical Medicine
Septic Shock
Bacteremia
Gynecology
Infertility
Morbidity
Wounds and Injuries
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Prophylactic antibiotics in gynecologic and obstetric surgery. / Hemsell, D. L.

In: Reviews of Infectious Diseases, Vol. 13, No. SUPPL. 10, 1991.

Research output: Contribution to journalArticle

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