Protein folding - Simplicity in complexity

M. M. Lin, A. H. Zewail

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Understanding and predicting protein folding would elucidate how misfolded proteins cause aggregation and amyloid formation, for example in Alzheimer's disease. Despite the seemingly bewildering complexity of protein biology, simple analytic models can still capture the basic physics and predict the fundamental limits for protein domain size and folding speed.

Original languageEnglish (US)
Pages (from-to)379-391
Number of pages13
JournalAnnalen der Physik
Volume524
Issue number8
DOIs
StatePublished - Aug 2012

Keywords

  • Protein folding problem
  • complexity reduced.

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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