Quality of life in patients with colorectal metastasis and intrahepatic chemotherapy

Sarah L. Blair, Marcia Grant, David Z J Chu, Carey Cullinane, Grace Dean, Roderich E. Schwarz, Lawrence Wagman

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Liver metastasis from colorectal cancer remains an oncological challenge. Hepatic chemotherapy has been used; however, rigorous quality of life (QOL) measurements are lacking. The aim of this study was to describe unique QOL issues to formulate a specific tool for this population. Methods: A purposive sample was identified of patients treated with intrahepatic chemotherapy. Consenting patients completed a demographic tool and the City of Hope QOL Scale/Cancer Patient survey. An in-depth interview on QOL concerns was conducted, taped, and transcribed verbatim. The data from the interviews were coded to identify recurrent themes. Results: Sixteen patients participated. Physical well-being was maintained. Significantly lower subscale scores were noted for psychological, social, and spiritual domains compared with nonpatient norms (City of Hope volunteers; n = 169). Patients found intrahepatic chemotherapy convenient but were unable to pursue vigorous activity, and their sleep habits changed. Psychologically, patients felt reassured to receive specific therapy to their liver. Conclusions: Pilot evaluation of QOL in this population revealed changes in physical, psychological, social, and spiritual dimensions. Both disease- and treatment-specific concerns were identified, and the results provide evidence for items to include in a QOL questionnaire specific to this population.

Original languageEnglish (US)
Pages (from-to)144-149
Number of pages6
JournalAnnals of Surgical Oncology
Volume10
Issue number2
DOIs
StatePublished - 2003

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Quality of Life
Neoplasm Metastasis
Drug Therapy
Hope
Liver
Interviews
Psychology
Population
Habits
Volunteers
Colorectal Neoplasms
Sleep
Demography
Therapeutics
Neoplasms
Surveys and Questionnaires

Keywords

  • Colorectal cancer
  • Liver metastasis
  • Quality of life
  • Regional chemotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Blair, S. L., Grant, M., Chu, D. Z. J., Cullinane, C., Dean, G., Schwarz, R. E., & Wagman, L. (2003). Quality of life in patients with colorectal metastasis and intrahepatic chemotherapy. Annals of Surgical Oncology, 10(2), 144-149. https://doi.org/10.1245/ASO.2003.03.060

Quality of life in patients with colorectal metastasis and intrahepatic chemotherapy. / Blair, Sarah L.; Grant, Marcia; Chu, David Z J; Cullinane, Carey; Dean, Grace; Schwarz, Roderich E.; Wagman, Lawrence.

In: Annals of Surgical Oncology, Vol. 10, No. 2, 2003, p. 144-149.

Research output: Contribution to journalArticle

Blair, SL, Grant, M, Chu, DZJ, Cullinane, C, Dean, G, Schwarz, RE & Wagman, L 2003, 'Quality of life in patients with colorectal metastasis and intrahepatic chemotherapy', Annals of Surgical Oncology, vol. 10, no. 2, pp. 144-149. https://doi.org/10.1245/ASO.2003.03.060
Blair, Sarah L. ; Grant, Marcia ; Chu, David Z J ; Cullinane, Carey ; Dean, Grace ; Schwarz, Roderich E. ; Wagman, Lawrence. / Quality of life in patients with colorectal metastasis and intrahepatic chemotherapy. In: Annals of Surgical Oncology. 2003 ; Vol. 10, No. 2. pp. 144-149.
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