Radiotherapy and immune checkpoint blockade: Potential interactions and future directions

David C. Binder, Yang Xin Fu, Ralph R. Weichselbaum

Research output: Contribution to journalShort survey

17 Citations (Scopus)

Abstract

Combining radiation and immune checkpoint blockade provides synergistic antitumor responses in animal models and a small subset of patients. New preclinical data have provided mechanistic insight into this treatment interaction and identification of therapeutic targets to optimize this approach.

Original languageEnglish (US)
Pages (from-to)463-465
Number of pages3
JournalTrends in Molecular Medicine
Volume21
Issue number8
DOIs
StatePublished - Jan 1 2015

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Radiotherapy
Animal Models
Radiation
Therapeutics
Direction compound

Keywords

  • Cancer
  • Immunotherapy
  • Radiation

ASJC Scopus subject areas

  • Molecular Biology
  • Molecular Medicine
  • Medicine(all)

Cite this

Radiotherapy and immune checkpoint blockade : Potential interactions and future directions. / Binder, David C.; Fu, Yang Xin; Weichselbaum, Ralph R.

In: Trends in Molecular Medicine, Vol. 21, No. 8, 01.01.2015, p. 463-465.

Research output: Contribution to journalShort survey

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