Readers of histone modifications

Miyong Yun, Jun Wu, Jerry L. Workman, Bing Li

Research output: Contribution to journalArticle

299 Scopus citations

Abstract

Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as epigenetic marks. Accumulating evidence suggests that the key function of histone modifications is to signal for recruitment or activity of downstream effectors. Here, we discuss the latest discovery of histone-modification readers and how the modification language is interpreted.

Original languageEnglish (US)
Pages (from-to)564-578
Number of pages15
JournalCell Research
Volume21
Issue number4
DOIs
Publication statusPublished - Apr 2011

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Keywords

  • chromatin
  • epigenetics
  • histone modification

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Yun, M., Wu, J., Workman, J. L., & Li, B. (2011). Readers of histone modifications. Cell Research, 21(4), 564-578. https://doi.org/10.1038/cr.2011.42