Real-time interactive, duplex MR measurements

Application in neurovascular imaging

S. G. Wetzel, V. S. Lee, A. G S Tan, O. Heid, S. Cha, G. Johnson, N. M. Rofsky

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

OBJECTIVE. Real-time interactive duplex MR imaging is a new phase-contrast MR imaging technique that enables the quantification and display of flow velocities in real time without the need for cardiac gating. We investigated the feasibility and reliability of the technique to assess hemodynamic information both in vitro and in vivo in the carotid arteries and in the venous sinuses. SUBJECTS AND METHODS. Real-time interactive duplex MR measurements (TR/TE, 53/27; flip angle, 90° encoding velocity, 100 or 150 cm/sec) were performed in vitro with a steady-flow phantom and in 10 healthy volunteers in whom common and internal carotid artery velocities were measured. In eight volunteers, velocity measurements were also performed in the superior sagittal sinus during both normal breathing and hyperventilation. Time-velocity plots were analyzed qualitatively and quantitatively and compared with findings from conventional segmented k-space phase-contrast MR imaging and Doppler sonography. RESULTS. Velocity determinations for real-time duplex MR and conventional phase-contrast MR imaging showed an in vitro correlation of 0.99 and an in vivo correlation of 0.83 (carotid arteries) and 0.76 (venous sinus). Velocity measurements in the carotid arteries with real-time MR imaging were significantly lower than those obtained with conventional phase-contrast MR (averaged, 7.8%: p = 0.003) or sonography (23.7%, p < 0.001), likely because of volume averaging. Small but significant velocity changes occurring in the venous sinus during hyperventilation were reliably identified with both MR techniques. CONCLUSION. Real-time interactive duplex MR imaging can be effectively applied in neurovascular imaging to obtain hemodynamic information.

Original languageEnglish (US)
Pages (from-to)703-707
Number of pages5
JournalAmerican Journal of Roentgenology
Volume177
Issue number3
StatePublished - 2001

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Carotid Arteries
Hyperventilation
Hemodynamics
Superior Sagittal Sinus
Doppler Ultrasonography
Common Carotid Artery
Internal Carotid Artery
Volunteers
Ultrasonography
Healthy Volunteers
Respiration
In Vitro Techniques

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Wetzel, S. G., Lee, V. S., Tan, A. G. S., Heid, O., Cha, S., Johnson, G., & Rofsky, N. M. (2001). Real-time interactive, duplex MR measurements: Application in neurovascular imaging. American Journal of Roentgenology, 177(3), 703-707.

Real-time interactive, duplex MR measurements : Application in neurovascular imaging. / Wetzel, S. G.; Lee, V. S.; Tan, A. G S; Heid, O.; Cha, S.; Johnson, G.; Rofsky, N. M.

In: American Journal of Roentgenology, Vol. 177, No. 3, 2001, p. 703-707.

Research output: Contribution to journalArticle

Wetzel, SG, Lee, VS, Tan, AGS, Heid, O, Cha, S, Johnson, G & Rofsky, NM 2001, 'Real-time interactive, duplex MR measurements: Application in neurovascular imaging', American Journal of Roentgenology, vol. 177, no. 3, pp. 703-707.
Wetzel SG, Lee VS, Tan AGS, Heid O, Cha S, Johnson G et al. Real-time interactive, duplex MR measurements: Application in neurovascular imaging. American Journal of Roentgenology. 2001;177(3):703-707.
Wetzel, S. G. ; Lee, V. S. ; Tan, A. G S ; Heid, O. ; Cha, S. ; Johnson, G. ; Rofsky, N. M. / Real-time interactive, duplex MR measurements : Application in neurovascular imaging. In: American Journal of Roentgenology. 2001 ; Vol. 177, No. 3. pp. 703-707.
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abstract = "OBJECTIVE. Real-time interactive duplex MR imaging is a new phase-contrast MR imaging technique that enables the quantification and display of flow velocities in real time without the need for cardiac gating. We investigated the feasibility and reliability of the technique to assess hemodynamic information both in vitro and in vivo in the carotid arteries and in the venous sinuses. SUBJECTS AND METHODS. Real-time interactive duplex MR measurements (TR/TE, 53/27; flip angle, 90° encoding velocity, 100 or 150 cm/sec) were performed in vitro with a steady-flow phantom and in 10 healthy volunteers in whom common and internal carotid artery velocities were measured. In eight volunteers, velocity measurements were also performed in the superior sagittal sinus during both normal breathing and hyperventilation. Time-velocity plots were analyzed qualitatively and quantitatively and compared with findings from conventional segmented k-space phase-contrast MR imaging and Doppler sonography. RESULTS. Velocity determinations for real-time duplex MR and conventional phase-contrast MR imaging showed an in vitro correlation of 0.99 and an in vivo correlation of 0.83 (carotid arteries) and 0.76 (venous sinus). Velocity measurements in the carotid arteries with real-time MR imaging were significantly lower than those obtained with conventional phase-contrast MR (averaged, 7.8{\%}: p = 0.003) or sonography (23.7{\%}, p < 0.001), likely because of volume averaging. Small but significant velocity changes occurring in the venous sinus during hyperventilation were reliably identified with both MR techniques. CONCLUSION. Real-time interactive duplex MR imaging can be effectively applied in neurovascular imaging to obtain hemodynamic information.",
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AU - Johnson, G.

AU - Rofsky, N. M.

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N2 - OBJECTIVE. Real-time interactive duplex MR imaging is a new phase-contrast MR imaging technique that enables the quantification and display of flow velocities in real time without the need for cardiac gating. We investigated the feasibility and reliability of the technique to assess hemodynamic information both in vitro and in vivo in the carotid arteries and in the venous sinuses. SUBJECTS AND METHODS. Real-time interactive duplex MR measurements (TR/TE, 53/27; flip angle, 90° encoding velocity, 100 or 150 cm/sec) were performed in vitro with a steady-flow phantom and in 10 healthy volunteers in whom common and internal carotid artery velocities were measured. In eight volunteers, velocity measurements were also performed in the superior sagittal sinus during both normal breathing and hyperventilation. Time-velocity plots were analyzed qualitatively and quantitatively and compared with findings from conventional segmented k-space phase-contrast MR imaging and Doppler sonography. RESULTS. Velocity determinations for real-time duplex MR and conventional phase-contrast MR imaging showed an in vitro correlation of 0.99 and an in vivo correlation of 0.83 (carotid arteries) and 0.76 (venous sinus). Velocity measurements in the carotid arteries with real-time MR imaging were significantly lower than those obtained with conventional phase-contrast MR (averaged, 7.8%: p = 0.003) or sonography (23.7%, p < 0.001), likely because of volume averaging. Small but significant velocity changes occurring in the venous sinus during hyperventilation were reliably identified with both MR techniques. CONCLUSION. Real-time interactive duplex MR imaging can be effectively applied in neurovascular imaging to obtain hemodynamic information.

AB - OBJECTIVE. Real-time interactive duplex MR imaging is a new phase-contrast MR imaging technique that enables the quantification and display of flow velocities in real time without the need for cardiac gating. We investigated the feasibility and reliability of the technique to assess hemodynamic information both in vitro and in vivo in the carotid arteries and in the venous sinuses. SUBJECTS AND METHODS. Real-time interactive duplex MR measurements (TR/TE, 53/27; flip angle, 90° encoding velocity, 100 or 150 cm/sec) were performed in vitro with a steady-flow phantom and in 10 healthy volunteers in whom common and internal carotid artery velocities were measured. In eight volunteers, velocity measurements were also performed in the superior sagittal sinus during both normal breathing and hyperventilation. Time-velocity plots were analyzed qualitatively and quantitatively and compared with findings from conventional segmented k-space phase-contrast MR imaging and Doppler sonography. RESULTS. Velocity determinations for real-time duplex MR and conventional phase-contrast MR imaging showed an in vitro correlation of 0.99 and an in vivo correlation of 0.83 (carotid arteries) and 0.76 (venous sinus). Velocity measurements in the carotid arteries with real-time MR imaging were significantly lower than those obtained with conventional phase-contrast MR (averaged, 7.8%: p = 0.003) or sonography (23.7%, p < 0.001), likely because of volume averaging. Small but significant velocity changes occurring in the venous sinus during hyperventilation were reliably identified with both MR techniques. CONCLUSION. Real-time interactive duplex MR imaging can be effectively applied in neurovascular imaging to obtain hemodynamic information.

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