Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

Jin U. Kang, Yong Huang, Kang Zhang, Zuhaib Ibrahim, Jaepyeong Cha, W. P.Andrew Lee, Gerald Brandacher, Peter L. Gehlbach

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourierdomain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10 volume/s for an image volume size of 160 × 80 × 1024 (X × Y × Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter < 0.8 mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter ~0.1 mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment.

Original languageEnglish (US)
Article number081403
JournalJournal of biomedical optics
Volume17
Issue number8
DOIs
StatePublished - Aug 1 2012
Externally publishedYes

Fingerprint

Optical tomography
tomography
arterioles
retina
arteries
rats
vessels
Rats
isolation
surgeons
maneuvers
display devices
Imaging systems
Program processors
image processing
Image processing
Visualization
Pixels
pixels
Imaging techniques

Keywords

  • Fiber optic sensor
  • Medical optics instrumentation
  • Optical coherence tomography
  • Optical imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

Cite this

Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries. / Kang, Jin U.; Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W. P.Andrew; Brandacher, Gerald; Gehlbach, Peter L.

In: Journal of biomedical optics, Vol. 17, No. 8, 081403, 01.08.2012.

Research output: Contribution to journalArticle

Kang, Jin U. ; Huang, Yong ; Zhang, Kang ; Ibrahim, Zuhaib ; Cha, Jaepyeong ; Lee, W. P.Andrew ; Brandacher, Gerald ; Gehlbach, Peter L. / Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries. In: Journal of biomedical optics. 2012 ; Vol. 17, No. 8.
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