Receptor-mediated endocytosis and the structural organization of the cell membrane

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Abstract

Receptor-mediated endocytosis is a general biological process by which animal cells take up selected macromolecules from extracellular fluid. These molecules bind to cell surface receptors and enter cells when the plasma membrane invaginates and pinches off to form an endocytic vesicle. Mutations that disrupt the receptor-mediated endocytosis of plasma low density lipoprotein are a frequent cause of atherosclerosis and myocardial infarction in man.

Original languageEnglish (US)
Title of host publicationNational Cancer Institute Monograph
Pages3-6
Number of pages4
VolumeNo. 60
Publication statusPublished - 1982

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ASJC Scopus subject areas

  • Cancer Research
  • Medicine(all)

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