@article{b21b5b0415644eb2b3c3e2dba52b1654,
title = "Regulation of human fetal testicular secretion of testosterone: Low-density lipoprotein-cholesterol and cholesterol synthesized de novo as steroid precursor",
abstract = "The results of the present investigation support the conclusion that low-density lipoprotein (LDL)-cholesterol facilitates androgen synthesis in human chorionic gonadotropin (hCG)-treated human fetal testicular tissue in vitro. Moreover, the number of LDL receptors and the rate of de novo synthesis of cholesterol are high during the period of active fetal testicular steroidogenesis and fall with advancing gestational age, suggestive of regulation by hCG.",
author = "Carr, {Bruce R.} and Parker, {C. Richard} and Masao Ohashi and MacDonald, {Paul C.} and Simpson, {Evan R.}",
note = "Funding Information: From The Cecil H. and Ida Green Center for Reproductive Biology Sczences and the Departments of Obstetrics and Gynecology and Biochemistry, The l'ninersi~ of Texas Southwestern Medical School. Supported tn part United States Public Health Service Grants 5-ROl-HD13234,5-ROl -HDl4513, and 5-PSO-HDI 1149. Certificate of Merit Award presented at the Fiftieth Annual Meeting of The Cm&al Association of Obstetricialw and Gynecologists, San Antonio, Texas, October 14-16, 1982. Rrpint requests: Bruce R. Carr, M.D., Department of Obstetrics and Gynecology, The Unisersity of TPX~J Southwestern Medical School, 5323 Ha? Hines Blvd., Dallas, Texas 75235.",
year = "1983",
month = jun,
day = "1",
doi = "10.1016/0002-9378(83)90743-3",
language = "English (US)",
volume = "146",
pages = "241--247",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "3",
}