Relocating job wise? A mathematical model separates quantitatively the cytostatic and cytotoxic effects of a HER2 tyrosine kinase inhibitor

Medicine & Life Sciences

• Lapatinib 100%
• Cytostatic Agents 80%
• Protein-Tyrosine Kinases 64%
• Theoretical Models 57%
• Proto-Oncogenes 20%
• Gene Amplification 20%
• G1 Phase 18%
• Tumor Suppressor Genes 17%
• Oncogenes 16%
• Cell Cycle 13%
• Breast 13%
• Cell Count 13%
• Kinetics 12%
• Epithelial Cells 12%
• Cell Proliferation 11%
• Breast Neoplasms 11%
• Mutation 9%
• Growth 8%
• Pharmaceutical Preparations 7%
• Therapeutics 5%

Mathematics

• Inhibitor 88%
• Mathematical Model 52%
• Experimental Data 35%
• Cell 26%
• Cell Proliferation 25%
• Cell Cycle 23%
• Breast Cancer 21%
• Amplification 21%
• Therapy 20%
• Saturation 18%
• Drugs 18%
• Mutation 17%
• Model 17%
• Gene 17%
• Molecules 17%
• Kinetics 16%
• Human 15%
• Background 15%
• Strategy 12%

Engineering & Materials Science

• Mathematical models 48%
• Gene Amplification 47%
• Epithelial Cells 36%
• Cell proliferation 34%
• Molecules 22%
• Cells 22%