Renal cell carcinoma with translocation (X;1) Further evidence for a cytogenetically defined subtype

Vijay Tonk, Kathleen S. Wilson, Charles F. Timmons, Nancy R. Schneider, Gail E. Tomlinson

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

A renal cell carcinoma from a 15-year-old male had a 49,Yt(X;1)(p11.2;g21), +der(X)t(X;1) (p11.2;q21), +5, -16, +17, +18 karyotype. This is the third report of a tronslocation involving a breakpoint at Xp11.2 in a renal cell carcinoma in a child. A total of nine cases of renal cell carcinoma involving Xp11, including this case, have been reported. Of the eight cases for which there are genetics reports, all are male. Patients with renal cell carcinoma with abnormalities at Xp11 appear to be younger than renal cell carcinoma patients overall.

Original languageEnglish (US)
Pages (from-to)72-75
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume81
Issue number1
DOIs
StatePublished - May 1995

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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