A total of 60 patients (71 renal units) with grade 2/5 vesicoureteral reflux into the lower pole moiety of a completely duplicated system was managed by medical surveillance and is compared to an identically managed age, race and sex matched control population with a similar degree of reflux into a single collecting system. During a median 2-year observation period reflux ceased spontaneously in 10% of the patients with duplication compared to 35% of the control population (p <0.01). Comparisons between the 2 study groups failed to reveal a difference in the incidence of break-through urinary tract infections, advancing degrees of reflux and/or the development or progression of renal scarring (p>0.5). Despite the fact that the resolution rate in duplex systems is significantly lower than that of a single system, it is apparent that cessation of grade 2/5 reflux into a duplicated ureter will occur and that a trial of medical management is an appropriate initial method of therapy.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of Urology|
|Publication status||Published - Jan 1 1991|
- Urinary tract
- Vesico-ureteral reflux
ASJC Scopus subject areas