Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts: Insights from a Multicenter U.S. Registry

Peter Tajti, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A. Jaffer, Robert W. Yeh, Mitul Patel, Ehtisham Mahmud, James W. Choi, Anthony H. Doing, Catalin Toma, Barry Uretsky, Santiago Garcia, Jeffrey W. Moses, Manish Parikh, Ajay Kirtane, Ziad A. Ali, Raja Hatem, Judit Karacsonyi, Barbara A. DanekBavana V. Rangan, Subhash Banerjee, Imre Ungi, Emmanouil S. Brilakis

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2.02%) performed at 18 United States centers. The mean age of the study patients was 69 ± 7 years and 95% were men. The most common CTO target vessel was the right coronary artery (55%). The mean J-CTO score in the LIMA group was high (3.45 ± 0.76). The technical success rates were 70% for retrograde PCI via LIMA graft vs 81.05% for retrograde via other conduits (P≤.25), while procedural success rates were 70% for retrograde PCI via LIMA graft and 78.19% for retrograde via other conduits (P≤.41). The incidence of major in-hospital complications was also similar between the LIMA and non-LIMA retrograde groups (5% vs 6%; P>.99). Use of guide-catheter extensions (40% vs 28%; P≤.22), intravascular ultrasound (45% vs 31%; P≤.20), and left ventricular assist devices (24% vs 10%; P≤.08) was numerically higher in retrograde CTO-PCIs via LIMA grafts. CONCLUSIONS: Retrograde CTO-PCI is infrequently performed via LIMA grafts and is associated with similar success and major in-hospital complication rates as retrograde CTO-PCI performed via other conduits.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalJournal of Invasive Cardiology
Volume30
Issue number3
StatePublished - Mar 1 2018

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Mammary Arteries
Percutaneous Coronary Intervention
Registries
Coronary Vessels
Transplants
Heart-Assist Devices
Catheters

Keywords

  • chronic total occlusion
  • left internal mammary artery graft
  • LIMA
  • retrograde PCI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts : Insights from a Multicenter U.S. Registry. / Tajti, Peter; Karatasakis, Aris; Karmpaliotis, Dimitri; Alaswad, Khaldoon; Jaffer, Farouc A.; Yeh, Robert W.; Patel, Mitul; Mahmud, Ehtisham; Choi, James W.; Doing, Anthony H.; Toma, Catalin; Uretsky, Barry; Garcia, Santiago; Moses, Jeffrey W.; Parikh, Manish; Kirtane, Ajay; Ali, Ziad A.; Hatem, Raja; Karacsonyi, Judit; Danek, Barbara A.; Rangan, Bavana V.; Banerjee, Subhash; Ungi, Imre; Brilakis, Emmanouil S.

In: Journal of Invasive Cardiology, Vol. 30, No. 3, 01.03.2018, p. 89-96.

Research output: Contribution to journalArticle

Tajti, P, Karatasakis, A, Karmpaliotis, D, Alaswad, K, Jaffer, FA, Yeh, RW, Patel, M, Mahmud, E, Choi, JW, Doing, AH, Toma, C, Uretsky, B, Garcia, S, Moses, JW, Parikh, M, Kirtane, A, Ali, ZA, Hatem, R, Karacsonyi, J, Danek, BA, Rangan, BV, Banerjee, S, Ungi, I & Brilakis, ES 2018, 'Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts: Insights from a Multicenter U.S. Registry', Journal of Invasive Cardiology, vol. 30, no. 3, pp. 89-96.
Tajti, Peter ; Karatasakis, Aris ; Karmpaliotis, Dimitri ; Alaswad, Khaldoon ; Jaffer, Farouc A. ; Yeh, Robert W. ; Patel, Mitul ; Mahmud, Ehtisham ; Choi, James W. ; Doing, Anthony H. ; Toma, Catalin ; Uretsky, Barry ; Garcia, Santiago ; Moses, Jeffrey W. ; Parikh, Manish ; Kirtane, Ajay ; Ali, Ziad A. ; Hatem, Raja ; Karacsonyi, Judit ; Danek, Barbara A. ; Rangan, Bavana V. ; Banerjee, Subhash ; Ungi, Imre ; Brilakis, Emmanouil S. / Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts : Insights from a Multicenter U.S. Registry. In: Journal of Invasive Cardiology. 2018 ; Vol. 30, No. 3. pp. 89-96.
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abstract = "BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2.02{\%}) performed at 18 United States centers. The mean age of the study patients was 69 ± 7 years and 95{\%} were men. The most common CTO target vessel was the right coronary artery (55{\%}). The mean J-CTO score in the LIMA group was high (3.45 ± 0.76). The technical success rates were 70{\%} for retrograde PCI via LIMA graft vs 81.05{\%} for retrograde via other conduits (P≤.25), while procedural success rates were 70{\%} for retrograde PCI via LIMA graft and 78.19{\%} for retrograde via other conduits (P≤.41). The incidence of major in-hospital complications was also similar between the LIMA and non-LIMA retrograde groups (5{\%} vs 6{\%}; P>.99). Use of guide-catheter extensions (40{\%} vs 28{\%}; P≤.22), intravascular ultrasound (45{\%} vs 31{\%}; P≤.20), and left ventricular assist devices (24{\%} vs 10{\%}; P≤.08) was numerically higher in retrograde CTO-PCIs via LIMA grafts. CONCLUSIONS: Retrograde CTO-PCI is infrequently performed via LIMA grafts and is associated with similar success and major in-hospital complication rates as retrograde CTO-PCI performed via other conduits.",
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T1 - Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts

T2 - Insights from a Multicenter U.S. Registry

AU - Tajti, Peter

AU - Karatasakis, Aris

AU - Karmpaliotis, Dimitri

AU - Alaswad, Khaldoon

AU - Jaffer, Farouc A.

AU - Yeh, Robert W.

AU - Patel, Mitul

AU - Mahmud, Ehtisham

AU - Choi, James W.

AU - Doing, Anthony H.

AU - Toma, Catalin

AU - Uretsky, Barry

AU - Garcia, Santiago

AU - Moses, Jeffrey W.

AU - Parikh, Manish

AU - Kirtane, Ajay

AU - Ali, Ziad A.

AU - Hatem, Raja

AU - Karacsonyi, Judit

AU - Danek, Barbara A.

AU - Rangan, Bavana V.

AU - Banerjee, Subhash

AU - Ungi, Imre

AU - Brilakis, Emmanouil S.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2.02%) performed at 18 United States centers. The mean age of the study patients was 69 ± 7 years and 95% were men. The most common CTO target vessel was the right coronary artery (55%). The mean J-CTO score in the LIMA group was high (3.45 ± 0.76). The technical success rates were 70% for retrograde PCI via LIMA graft vs 81.05% for retrograde via other conduits (P≤.25), while procedural success rates were 70% for retrograde PCI via LIMA graft and 78.19% for retrograde via other conduits (P≤.41). The incidence of major in-hospital complications was also similar between the LIMA and non-LIMA retrograde groups (5% vs 6%; P>.99). Use of guide-catheter extensions (40% vs 28%; P≤.22), intravascular ultrasound (45% vs 31%; P≤.20), and left ventricular assist devices (24% vs 10%; P≤.08) was numerically higher in retrograde CTO-PCIs via LIMA grafts. CONCLUSIONS: Retrograde CTO-PCI is infrequently performed via LIMA grafts and is associated with similar success and major in-hospital complication rates as retrograde CTO-PCI performed via other conduits.

AB - BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2.02%) performed at 18 United States centers. The mean age of the study patients was 69 ± 7 years and 95% were men. The most common CTO target vessel was the right coronary artery (55%). The mean J-CTO score in the LIMA group was high (3.45 ± 0.76). The technical success rates were 70% for retrograde PCI via LIMA graft vs 81.05% for retrograde via other conduits (P≤.25), while procedural success rates were 70% for retrograde PCI via LIMA graft and 78.19% for retrograde via other conduits (P≤.41). The incidence of major in-hospital complications was also similar between the LIMA and non-LIMA retrograde groups (5% vs 6%; P>.99). Use of guide-catheter extensions (40% vs 28%; P≤.22), intravascular ultrasound (45% vs 31%; P≤.20), and left ventricular assist devices (24% vs 10%; P≤.08) was numerically higher in retrograde CTO-PCIs via LIMA grafts. CONCLUSIONS: Retrograde CTO-PCI is infrequently performed via LIMA grafts and is associated with similar success and major in-hospital complication rates as retrograde CTO-PCI performed via other conduits.

KW - chronic total occlusion

KW - left internal mammary artery graft

KW - LIMA

KW - retrograde PCI

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