Ruthenium catalyzed synthesis of enaminones

Naga Durgarao Koduri, Halee Scott, Bethany Hileman, Justin D. Cox, Michael Coffin, Lindsay Glicksberg, Syed R. Hussaini

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

The Grubbs first-generation catalyst has been found to be an effective catalyst for the synthesis of enaminones by coupling thioamides with α-diazodicarbonyl compounds. The reaction is successful in converting primary, secondary, and tertiary thioamides into their corresponding enaminones. The reaction is also suitable for the synthesis of chiral enaminones.

Original languageEnglish (US)
Pages (from-to)440-443
Number of pages4
JournalOrganic Letters
Volume14
Issue number2
DOIs
StatePublished - Jan 20 2012
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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  • Cite this

    Koduri, N. D., Scott, H., Hileman, B., Cox, J. D., Coffin, M., Glicksberg, L., & Hussaini, S. R. (2012). Ruthenium catalyzed synthesis of enaminones. Organic Letters, 14(2), 440-443. https://doi.org/10.1021/ol202812d