Salt and nephrolithiasis

Andrea Ticinesi, Antonio Nouvenne, Naim M. Maalouf, Loris Borghi, Tiziana Meschi

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations

Abstract

Dietary sodium chloride intake is nowadays globally known as one of the major threats for cardiovascular health. However, there is also important evidence that it may influence idiopathic calcium nephrolithiasis onset and recurrence. Higher salt intake has been associated with hypercalciuria and hypocitraturia, which are major risk factors for calcium stone formation. Dietary salt restriction can be an effective means for secondary prevention of nephrolithiasis as well. Thus in this paper, we review the complex relationship between salt and nephrolithiasis, pointing out the difference between dietary sodium and salt intake and the best methods to assess them, highlighting the main findings of epidemiologic, laboratory and intervention studies and focusing on open issues such as the role of dietary salt in secondary causes of nephrolithiasis.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalNephrology Dialysis Transplantation
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • hypercalciuria
  • nephrolithiasis
  • salt
  • urinary calcium
  • urinary sodium

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

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