Scalable, transition-metal-free direct oxime O-arylation: rapid access to O-arylhydroxylamines and substituted benzo[b]furans

Hongyin Gao, Qing Long Xu, Craig Keene, László Kürti

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

O-aryloximes, generated from readily available and inexpensive oximes through transition-metal-free O-arylation, can either be hydrolyzed to O-arylhydroxylamines or conveniently converted to structurally diverse benzo[b]furans through an environmentally benign, one-pot [3,3]-sigmatropic rearrangement/cyclization sequence.

Original languageEnglish (US)
Pages (from-to)8883-8887
Number of pages5
JournalChemistry (Weinheim an der Bergstrasse, Germany)
Volume20
Issue number29
DOIs
StatePublished - Jul 14 2014

Fingerprint

Oximes
Cyclization
Transition metals
Metals
benzofuran

Keywords

  • benzofurans
  • cyclization
  • diaryliodonium salts
  • O-arylation
  • oximes
  • sigmatropic rearrangement
  • transition-metal free

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Scalable, transition-metal-free direct oxime O-arylation : rapid access to O-arylhydroxylamines and substituted benzo[b]furans. / Gao, Hongyin; Xu, Qing Long; Keene, Craig; Kürti, László.

In: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 20, No. 29, 14.07.2014, p. 8883-8887.

Research output: Contribution to journalArticle

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