Abstract
The adsorption chromatography of purines and related heterocyclic compounds on Sephadex G-10 was investigated under different conditions of pH, ionic strength and flow rate and found to give excellent separations. The elution volumes were highly reproducible and recovery quantitative. A relation between a log function of the elution volumes and substituents on the purine ring was shown and the additivity of the resulting Δ log V6° values used to predict elution volumes. Some analytical and preparative applications have been undertaken.
Original language | English (US) |
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Pages (from-to) | 662-675 |
Number of pages | 14 |
Journal | Journal of Chromatography A |
Volume | 32 |
Issue number | C |
DOIs | |
State | Published - 1968 |
Externally published | Yes |
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Organic Chemistry