Septins Set the Stage for Orai1 to Bind STIM1 at ER-PM Junctions

Jen Liou, Tobias Meyer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The endoplasmic reticulum (ER) Ca2+ sensor STIM1 recruits and activates the plasma membrane (PM) Ca2+ channel Orai1 at ER-PM junctions for store-operated Ca2+ entry (SOCE). Reporting in Nature, Sharma etal. (2013) showed that septins are necessary for Orai1 recruitment and SOCE, implicating these scaffolding proteins in signaling at ER-PM junctions.

Original languageEnglish (US)
Pages (from-to)116-118
Number of pages3
JournalDevelopmental Cell
Volume26
Issue number2
DOIs
StatePublished - Jul 29 2013

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Septins
Cell membranes
Endoplasmic Reticulum
Cell Membrane
Ion Channels
Sensors
Proteins

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Septins Set the Stage for Orai1 to Bind STIM1 at ER-PM Junctions. / Liou, Jen; Meyer, Tobias.

In: Developmental Cell, Vol. 26, No. 2, 29.07.2013, p. 116-118.

Research output: Contribution to journalArticle

Liou, Jen ; Meyer, Tobias. / Septins Set the Stage for Orai1 to Bind STIM1 at ER-PM Junctions. In: Developmental Cell. 2013 ; Vol. 26, No. 2. pp. 116-118.
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