Seroepidemiology of the group-A streptococcal carriage state in a private pediatric practice

C. M. Ginsburg, G. H. McCracken, S. D. Crow, B. R. Dildy, G. Morchower, J. B. Steinberg, K. Lancaster

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Abstract

During a 24-month period, throat-swab cultures were obtained on 1,362 well children who were 3 months to 14 years of age. The overall incidence of positive cultures for group-A β-hemolytic Streptococcus was 3.3%; in those children older than 1 year, it was 4.4%. The largest incidence of positive cultures occurred in the 5- to 7-year-old (8.3%) and 8- to 10-year-old (4.5%) age groups. No positive cultures were obtained from 339 infants younger than 1 year of age. There was no relation between positive cultures and the month of the year. There were no significant differences between the age, sex, presence of tonsils, previous group-A streptococcal infections, or the presence in a daycare center or school of children with positive cultures compared with those children with negative cultures. Follow-ups were obtained on 29 of 45 children with positive throat cultures; all of the children were asymptomatic and had normal results of physical examinations. Group-A streptococci of the same serotype as the original isolate were isolated from 19 of these children. Three to four days after a ten-day course of erythromycin estolate, five of 19 children again had positive cultures. Twenty-six of the 29 children had a total of 43 siblings residing in the home. Serotypically identical group-A streptococci were isolated from five siblings (11%). Only one of 29 patients from whom paired serum samples were obtained showed a fourfold rise or fall in the Streptozyme titers.

Original languageEnglish (US)
Pages (from-to)614-617
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume139
Issue number6
StatePublished - 1985

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Private Practice
Pediatrics
Streptococcus
Pharynx
Siblings
Erythromycin Estolate
Streptococcal Infections
Palatine Tonsil
Incidence
Physical Examination
Age Groups

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Seroepidemiology of the group-A streptococcal carriage state in a private pediatric practice. / Ginsburg, C. M.; McCracken, G. H.; Crow, S. D.; Dildy, B. R.; Morchower, G.; Steinberg, J. B.; Lancaster, K.

In: American Journal of Diseases of Children, Vol. 139, No. 6, 1985, p. 614-617.

Research output: Contribution to journalArticle

Ginsburg, CM, McCracken, GH, Crow, SD, Dildy, BR, Morchower, G, Steinberg, JB & Lancaster, K 1985, 'Seroepidemiology of the group-A streptococcal carriage state in a private pediatric practice', American Journal of Diseases of Children, vol. 139, no. 6, pp. 614-617.
Ginsburg, C. M. ; McCracken, G. H. ; Crow, S. D. ; Dildy, B. R. ; Morchower, G. ; Steinberg, J. B. ; Lancaster, K. / Seroepidemiology of the group-A streptococcal carriage state in a private pediatric practice. In: American Journal of Diseases of Children. 1985 ; Vol. 139, No. 6. pp. 614-617.
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