Severe pulmonary arterial hypertension: stratification of medical therapies, mechanical support, and lung transplantation

Research output: Contribution to journalArticle

1 Scopus citations


Severe pulmonary hypertension is recognized by focusing on the clinical signs and tests that demonstrate decompensated right ventricular failure or, in the worst-case scenario, shock. An aggressive treatment regimen including a prostacyclin infusion is required for these patients. Once admitted to the hospital, or the ICU for decompensated right ventricular failure, the short- and long-term outcomes for PAH patients are poor. For those who are candidates, urgent lung transplantation, or extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation may be rescue therapy.

Original languageEnglish (US)
Pages (from-to)347-356
Number of pages10
JournalHeart Failure Reviews
Issue number3
Publication statusPublished - May 1 2016



  • Acute right ventricular failure
  • ECMO
  • Lung transplantation
  • Pulmonary arterial hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this