Abstract
We describe the first severe systemic hypersensitivity reaction to ibuprofen in a pediatric patient with previously undiagnosed systemic lupus erythematosus (SLE). An 11-year-old Thai male presented with fever, rash, altered mental status, and hypotension after oral administration of ibuprofen leading to the diagnosis of SLE. Re-dosing with ibuprofen resulted in recurrence of presenting symptoms. Severe hypersensitivity with hypotension can be a rare consequence of the use of ibuprofen in children with collagen vascular disease. When encountered in an otherwise healthy child, a high index of suspicion must be maintained for the diagnosis of SLE.
Original language | English (US) |
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Pages (from-to) | 171-172 |
Number of pages | 2 |
Journal | Journal of Rheumatology |
Volume | 33 |
Issue number | 1 |
State | Published - Jan 2006 |
Keywords
- Collagen vascular disease
- Ibuprofen
- Pediatrics
- Severe hypersensitivity reaction
- Systemic lupus erythematosus
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology