Sex and Gender

Critical Variables in Pre-Clinical and Clinical Medical Research

Eugenia Morselli, Aaron P. Frank, Roberta S. Santos, Luciana A. Fátima, Biff F. Palmer, Deborah J. Clegg

Research output: Contribution to journalComment/debate

12 Citations (Scopus)

Abstract

In this Essay, we discuss the critical need to incorporate sex and gender in pre-clinical and clinical research to enhance our understanding of the mechanisms by which metabolic processes differ by sex and gender. This knowledge will allow for development of personalized medicine which will optimize therapies specific for individuals.

Original languageEnglish (US)
Pages (from-to)203-209
Number of pages7
JournalCell Metabolism
Volume24
Issue number2
DOIs
StatePublished - Aug 9 2016

Fingerprint

Biomedical Research
Precision Medicine
Research
Therapeutics

Keywords

  • cardiovascular diseases
  • chromosome
  • estrogens
  • gender
  • obesity
  • sex
  • testosterone
  • type 2 diabetes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

Cite this

Morselli, E., Frank, A. P., Santos, R. S., Fátima, L. A., Palmer, B. F., & Clegg, D. J. (2016). Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research. Cell Metabolism, 24(2), 203-209. https://doi.org/10.1016/j.cmet.2016.07.017

Sex and Gender : Critical Variables in Pre-Clinical and Clinical Medical Research. / Morselli, Eugenia; Frank, Aaron P.; Santos, Roberta S.; Fátima, Luciana A.; Palmer, Biff F.; Clegg, Deborah J.

In: Cell Metabolism, Vol. 24, No. 2, 09.08.2016, p. 203-209.

Research output: Contribution to journalComment/debate

Morselli, E, Frank, AP, Santos, RS, Fátima, LA, Palmer, BF & Clegg, DJ 2016, 'Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research', Cell Metabolism, vol. 24, no. 2, pp. 203-209. https://doi.org/10.1016/j.cmet.2016.07.017
Morselli, Eugenia ; Frank, Aaron P. ; Santos, Roberta S. ; Fátima, Luciana A. ; Palmer, Biff F. ; Clegg, Deborah J. / Sex and Gender : Critical Variables in Pre-Clinical and Clinical Medical Research. In: Cell Metabolism. 2016 ; Vol. 24, No. 2. pp. 203-209.
@article{85ea37bc05784ce3b1acb1fdd0406546,
title = "Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research",
abstract = "In this Essay, we discuss the critical need to incorporate sex and gender in pre-clinical and clinical research to enhance our understanding of the mechanisms by which metabolic processes differ by sex and gender. This knowledge will allow for development of personalized medicine which will optimize therapies specific for individuals.",
keywords = "cardiovascular diseases, chromosome, estrogens, gender, obesity, sex, testosterone, type 2 diabetes",
author = "Eugenia Morselli and Frank, {Aaron P.} and Santos, {Roberta S.} and F{\'a}tima, {Luciana A.} and Palmer, {Biff F.} and Clegg, {Deborah J.}",
year = "2016",
month = "8",
day = "9",
doi = "10.1016/j.cmet.2016.07.017",
language = "English (US)",
volume = "24",
pages = "203--209",
journal = "Cell Metabolism",
issn = "1550-4131",
publisher = "Cell Press",
number = "2",

}

TY - JOUR

T1 - Sex and Gender

T2 - Critical Variables in Pre-Clinical and Clinical Medical Research

AU - Morselli, Eugenia

AU - Frank, Aaron P.

AU - Santos, Roberta S.

AU - Fátima, Luciana A.

AU - Palmer, Biff F.

AU - Clegg, Deborah J.

PY - 2016/8/9

Y1 - 2016/8/9

N2 - In this Essay, we discuss the critical need to incorporate sex and gender in pre-clinical and clinical research to enhance our understanding of the mechanisms by which metabolic processes differ by sex and gender. This knowledge will allow for development of personalized medicine which will optimize therapies specific for individuals.

AB - In this Essay, we discuss the critical need to incorporate sex and gender in pre-clinical and clinical research to enhance our understanding of the mechanisms by which metabolic processes differ by sex and gender. This knowledge will allow for development of personalized medicine which will optimize therapies specific for individuals.

KW - cardiovascular diseases

KW - chromosome

KW - estrogens

KW - gender

KW - obesity

KW - sex

KW - testosterone

KW - type 2 diabetes

UR - http://www.scopus.com/inward/record.url?scp=84991107024&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991107024&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2016.07.017

DO - 10.1016/j.cmet.2016.07.017

M3 - Comment/debate

VL - 24

SP - 203

EP - 209

JO - Cell Metabolism

JF - Cell Metabolism

SN - 1550-4131

IS - 2

ER -