Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research

Eugenia Morselli, Aaron P. Frank, Roberta S. Santos, Luciana A. Fátima, Biff F. Palmer, Deborah J. Clegg

Research output: Contribution to journalComment/debate

16 Scopus citations

Abstract

In this Essay, we discuss the critical need to incorporate sex and gender in pre-clinical and clinical research to enhance our understanding of the mechanisms by which metabolic processes differ by sex and gender. This knowledge will allow for development of personalized medicine which will optimize therapies specific for individuals.

Original languageEnglish (US)
Pages (from-to)203-209
Number of pages7
JournalCell Metabolism
Volume24
Issue number2
DOIs
StatePublished - Aug 9 2016

Keywords

  • cardiovascular diseases
  • chromosome
  • estrogens
  • gender
  • obesity
  • sex
  • testosterone
  • type 2 diabetes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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  • Cite this

    Morselli, E., Frank, A. P., Santos, R. S., Fátima, L. A., Palmer, B. F., & Clegg, D. J. (2016). Sex and Gender: Critical Variables in Pre-Clinical and Clinical Medical Research. Cell Metabolism, 24(2), 203-209. https://doi.org/10.1016/j.cmet.2016.07.017