Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent

Victoria Parish, Tarique Hussain, Philip Beerbaum, Gerald Greil, Eike Nagel, Reza Razavi, Tobias Schaeffter, Sergio Uribe

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Purpose: To evaluate the feasibility of a single breath-hold 3D cine balanced steady-state free precession (b-SSFP) sequence after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) injection for volumetric cardiac assessment. Materials and Methods: Fifteen adult patients routinely referred for cardiac magnetic resonance imaging (MRI) underwent quantitative ventricular volumetry on a clinical 1.5T MR-scanner using a 32-channel cardiac coil. A stack of 2D cine b-SSFP slices covering the ventricles was used as reference, followed by a single breath-hold 3D cine balanced SSFP protocol acquired before and after administration of Gd-DTPA. The acquisition was accelerated using SENSE in both phase encoding directions. Volumetric and contrast-to-noise data for each technique were assessed and compared. Results: The 3D cine protocol was accomplished within one breath-hold (mean acquisition time 20 sec; spatial resolution 2.1 × 2.1 × 10 mm; temporal resolution 51 msec). The contrast-to-noise ratio between blood and myocardium was 234 determined for the multiple 2D cine data, and could be increased for the 3D acquisition from 136 (3D precontrast) to 203 (3D postcontrast) after injecting Gd-DTPA. In addition the endocardial definition was significantly improved in postcontrast 3D cine b-SSFP. There was no significant difference for left and right ventricular volumes between standard 2D and 3D postcontrast cine b-SSFP. However, Bland-Altman plots showed greater bias and scatter when comparing 2D with 3D cine b-SSFP without contrast. Conclusion: 3D cine b-SSFP imaging of the heart using 32 channel coil technology and spatial undersampling allows reliable volumetric assessment within a single breath-hold after application of Gd-DTPA.

Original languageEnglish (US)
Pages (from-to)838-844
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume31
Issue number4
DOIs
StatePublished - Jan 1 2010

Fingerprint

Rubiaceae
Gadolinium
Acetic Acid
Contrast Media
Technology
Noise
Myocardium
Magnetic Resonance Imaging
Injections
diethylenetriamine

Keywords

  • 32-channel coil
  • 3D imaging
  • Ventricular volumes
  • Whole heart imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent. / Parish, Victoria; Hussain, Tarique; Beerbaum, Philip; Greil, Gerald; Nagel, Eike; Razavi, Reza; Schaeffter, Tobias; Uribe, Sergio.

In: Journal of Magnetic Resonance Imaging, Vol. 31, No. 4, 01.01.2010, p. 838-844.

Research output: Contribution to journalArticle

Parish, Victoria ; Hussain, Tarique ; Beerbaum, Philip ; Greil, Gerald ; Nagel, Eike ; Razavi, Reza ; Schaeffter, Tobias ; Uribe, Sergio. / Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent. In: Journal of Magnetic Resonance Imaging. 2010 ; Vol. 31, No. 4. pp. 838-844.
@article{fd84f7c1a18f452086c07c766b278762,
title = "Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent",
abstract = "Purpose: To evaluate the feasibility of a single breath-hold 3D cine balanced steady-state free precession (b-SSFP) sequence after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) injection for volumetric cardiac assessment. Materials and Methods: Fifteen adult patients routinely referred for cardiac magnetic resonance imaging (MRI) underwent quantitative ventricular volumetry on a clinical 1.5T MR-scanner using a 32-channel cardiac coil. A stack of 2D cine b-SSFP slices covering the ventricles was used as reference, followed by a single breath-hold 3D cine balanced SSFP protocol acquired before and after administration of Gd-DTPA. The acquisition was accelerated using SENSE in both phase encoding directions. Volumetric and contrast-to-noise data for each technique were assessed and compared. Results: The 3D cine protocol was accomplished within one breath-hold (mean acquisition time 20 sec; spatial resolution 2.1 × 2.1 × 10 mm; temporal resolution 51 msec). The contrast-to-noise ratio between blood and myocardium was 234 determined for the multiple 2D cine data, and could be increased for the 3D acquisition from 136 (3D precontrast) to 203 (3D postcontrast) after injecting Gd-DTPA. In addition the endocardial definition was significantly improved in postcontrast 3D cine b-SSFP. There was no significant difference for left and right ventricular volumes between standard 2D and 3D postcontrast cine b-SSFP. However, Bland-Altman plots showed greater bias and scatter when comparing 2D with 3D cine b-SSFP without contrast. Conclusion: 3D cine b-SSFP imaging of the heart using 32 channel coil technology and spatial undersampling allows reliable volumetric assessment within a single breath-hold after application of Gd-DTPA.",
keywords = "32-channel coil, 3D imaging, Ventricular volumes, Whole heart imaging",
author = "Victoria Parish and Tarique Hussain and Philip Beerbaum and Gerald Greil and Eike Nagel and Reza Razavi and Tobias Schaeffter and Sergio Uribe",
year = "2010",
month = "1",
day = "1",
doi = "10.1002/jmri.22061",
language = "English (US)",
volume = "31",
pages = "838--844",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Single breath-hold assessment of ventricular volumes using 32-channel coil technology and an extracellular contrast agent

AU - Parish, Victoria

AU - Hussain, Tarique

AU - Beerbaum, Philip

AU - Greil, Gerald

AU - Nagel, Eike

AU - Razavi, Reza

AU - Schaeffter, Tobias

AU - Uribe, Sergio

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Purpose: To evaluate the feasibility of a single breath-hold 3D cine balanced steady-state free precession (b-SSFP) sequence after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) injection for volumetric cardiac assessment. Materials and Methods: Fifteen adult patients routinely referred for cardiac magnetic resonance imaging (MRI) underwent quantitative ventricular volumetry on a clinical 1.5T MR-scanner using a 32-channel cardiac coil. A stack of 2D cine b-SSFP slices covering the ventricles was used as reference, followed by a single breath-hold 3D cine balanced SSFP protocol acquired before and after administration of Gd-DTPA. The acquisition was accelerated using SENSE in both phase encoding directions. Volumetric and contrast-to-noise data for each technique were assessed and compared. Results: The 3D cine protocol was accomplished within one breath-hold (mean acquisition time 20 sec; spatial resolution 2.1 × 2.1 × 10 mm; temporal resolution 51 msec). The contrast-to-noise ratio between blood and myocardium was 234 determined for the multiple 2D cine data, and could be increased for the 3D acquisition from 136 (3D precontrast) to 203 (3D postcontrast) after injecting Gd-DTPA. In addition the endocardial definition was significantly improved in postcontrast 3D cine b-SSFP. There was no significant difference for left and right ventricular volumes between standard 2D and 3D postcontrast cine b-SSFP. However, Bland-Altman plots showed greater bias and scatter when comparing 2D with 3D cine b-SSFP without contrast. Conclusion: 3D cine b-SSFP imaging of the heart using 32 channel coil technology and spatial undersampling allows reliable volumetric assessment within a single breath-hold after application of Gd-DTPA.

AB - Purpose: To evaluate the feasibility of a single breath-hold 3D cine balanced steady-state free precession (b-SSFP) sequence after gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA) injection for volumetric cardiac assessment. Materials and Methods: Fifteen adult patients routinely referred for cardiac magnetic resonance imaging (MRI) underwent quantitative ventricular volumetry on a clinical 1.5T MR-scanner using a 32-channel cardiac coil. A stack of 2D cine b-SSFP slices covering the ventricles was used as reference, followed by a single breath-hold 3D cine balanced SSFP protocol acquired before and after administration of Gd-DTPA. The acquisition was accelerated using SENSE in both phase encoding directions. Volumetric and contrast-to-noise data for each technique were assessed and compared. Results: The 3D cine protocol was accomplished within one breath-hold (mean acquisition time 20 sec; spatial resolution 2.1 × 2.1 × 10 mm; temporal resolution 51 msec). The contrast-to-noise ratio between blood and myocardium was 234 determined for the multiple 2D cine data, and could be increased for the 3D acquisition from 136 (3D precontrast) to 203 (3D postcontrast) after injecting Gd-DTPA. In addition the endocardial definition was significantly improved in postcontrast 3D cine b-SSFP. There was no significant difference for left and right ventricular volumes between standard 2D and 3D postcontrast cine b-SSFP. However, Bland-Altman plots showed greater bias and scatter when comparing 2D with 3D cine b-SSFP without contrast. Conclusion: 3D cine b-SSFP imaging of the heart using 32 channel coil technology and spatial undersampling allows reliable volumetric assessment within a single breath-hold after application of Gd-DTPA.

KW - 32-channel coil

KW - 3D imaging

KW - Ventricular volumes

KW - Whole heart imaging

UR - http://www.scopus.com/inward/record.url?scp=77950874456&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950874456&partnerID=8YFLogxK

U2 - 10.1002/jmri.22061

DO - 10.1002/jmri.22061

M3 - Article

C2 - 20373427

AN - SCOPUS:77950874456

VL - 31

SP - 838

EP - 844

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 4

ER -