@article{d3e534c421a543a39a88421ba8a1787d,
title = "Single-cell analysis of olfactory neurogenesis and differentiation in adult humans",
abstract = "The presence of active neurogenic niches in adult humans is controversial. We focused attention to the human olfactory neuroepithelium, an extracranial site supplying input to the olfactory bulbs of the brain. Using single-cell RNA sequencing analyzing 28,726 cells, we identified neural stem cell and neural progenitor cell pools and neurons. Additionally, we detailed the expression of 140 olfactory receptors. These data from the olfactory neuroepithelium niche provide evidence that neuron production may continue for decades in humans.",
author = "Durante, {Michael A.} and Stefan Kurtenbach and Sargi, {Zoukaa B.} and Harbour, {J. William} and Rhea Choi and Sarah Kurtenbach and Goss, {Garrett M.} and Hiroaki Matsunami and Goldstein, {Bradley J.}",
note = "Funding Information: We are grateful to the patients who generously contributed samples for this research. We acknowledge the assistance of the Onco-Genomics Shared Resource at the Sylvester Comprehensive Cancer Center and the University of Miami Center for Computational Science. This work was supported by funding from National Institutes of Health grant nos. DC013556 (B.J.G), DC016859 (B.J.G) and CA125970 (J.W.H.), the Triological Society/American College of Surgeons (B.J.G.), the University of Miami Sheila and David Fuente Graduate Program in Cancer Biology (M.A.D.) and the Center for Computational Science Fellowship (M.A.D.). The Sylvester Comprehensive Cancer Center also received funding from the National Cancer Institute Core Support Grant no. P30CA240139. Publisher Copyright: {\textcopyright} 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.",
year = "2020",
month = mar,
day = "1",
doi = "10.1038/s41593-020-0587-9",
language = "English (US)",
volume = "23",
pages = "323--326",
journal = "Nature neuroscience",
issn = "1097-6256",
publisher = "Nature Publishing Group",
number = "3",
}