Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone marrow and spinal cord while preserving peripheral regulatory mechanisms

Ding Chen, Monica Blazek, Sara Ireland, Sterling Ortega, Xiangmei Kong, Anouk Meeuwissen, Ann Stowe, Laura Carter, Yue Wang, Ronald Herbst, Nancy L. Monson

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Medicine & Life Sciences