Speech dysfluency exacerbated by levodopa in Parkinson's disease

Elan D. Louis, Linda Winfield, Stanley Fahn, Blair Ford

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

The role of dopamine in the modulation of speech fluency is complex. In this report we describe two patients with Parkinson's disease whose speech dysfluency was exacerbated by the administration of levodopa. In doing so, we extend the observation that dopaminergic mechanisms may be involved in the regulation of speech fluency. It is important for clinicians to recognize that, in some instances, dopaminergic replacement therapy may exacerbate an underlying dysfluency syndrome in PD.

Original languageEnglish (US)
Pages (from-to)562-565
Number of pages4
JournalMovement Disorders
Volume16
Issue number3
DOIs
StatePublished - May 2001

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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