Abstract
Chronic gastritis is an inflammatory condition of the gastric mucosa that may include structural alterations of the glandular compartment. The semiquantitative scoring systems advocated in the Sydney Systems and the subsequent Atrophy Club Guidelines remain essential for the recognition of the spectrum of the lesions detectable in gastric inflammatory disease. Most practicing pathologists, however, find them too cumbersome to use in their routine diagnostic activities. In this article, we propose a reporting system for chronic gastritis in staging and grading. Staging would convey information on the topography and extension of the gastric atrophic changes, whereas grading should represent the semiquantitative assessment of the combined severity of both mononuclear and granulocytic inflammation. This system could offer gastroenterologists a more immediate perception of the overall condition of the gastric mucosa while also providing useful information about gastric cancer risk.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 228-233 |
| Number of pages | 6 |
| Journal | Human Pathology |
| Volume | 36 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2005 |
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Keywords
- Gastritis
- Gastritis histology
- Staging and grading
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Staging and grading of chronic gastritis. / Rugge, Massimo; Genta, Robert M.
In: Human Pathology, Vol. 36, No. 3, 03.2005, p. 228-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Staging and grading of chronic gastritis
AU - Rugge, Massimo
AU - Genta, Robert M.
PY - 2005/3
Y1 - 2005/3
N2 - Chronic gastritis is an inflammatory condition of the gastric mucosa that may include structural alterations of the glandular compartment. The semiquantitative scoring systems advocated in the Sydney Systems and the subsequent Atrophy Club Guidelines remain essential for the recognition of the spectrum of the lesions detectable in gastric inflammatory disease. Most practicing pathologists, however, find them too cumbersome to use in their routine diagnostic activities. In this article, we propose a reporting system for chronic gastritis in staging and grading. Staging would convey information on the topography and extension of the gastric atrophic changes, whereas grading should represent the semiquantitative assessment of the combined severity of both mononuclear and granulocytic inflammation. This system could offer gastroenterologists a more immediate perception of the overall condition of the gastric mucosa while also providing useful information about gastric cancer risk.
AB - Chronic gastritis is an inflammatory condition of the gastric mucosa that may include structural alterations of the glandular compartment. The semiquantitative scoring systems advocated in the Sydney Systems and the subsequent Atrophy Club Guidelines remain essential for the recognition of the spectrum of the lesions detectable in gastric inflammatory disease. Most practicing pathologists, however, find them too cumbersome to use in their routine diagnostic activities. In this article, we propose a reporting system for chronic gastritis in staging and grading. Staging would convey information on the topography and extension of the gastric atrophic changes, whereas grading should represent the semiquantitative assessment of the combined severity of both mononuclear and granulocytic inflammation. This system could offer gastroenterologists a more immediate perception of the overall condition of the gastric mucosa while also providing useful information about gastric cancer risk.
KW - Gastritis
KW - Gastritis histology
KW - Staging and grading
UR - http://www.scopus.com/inward/record.url?scp=15544380448&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=15544380448&partnerID=8YFLogxK
U2 - 10.1016/j.humpath.2004.12.008
DO - 10.1016/j.humpath.2004.12.008
M3 - Article
C2 - 15791566
AN - SCOPUS:15544380448
VL - 36
SP - 228
EP - 233
JO - Human Pathology
JF - Human Pathology
SN - 0046-8177
IS - 3
ER -