Statistical Analysis Plan for “An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery”

Ian Yuan, Vanessa A. Olbrecht, Janell L. Mensinger, Bingqing Zhang, Andrew J. Davidson, Britta S. von Ungern-Sternberg, Justin Skowno, Qing Quan Lian, Xing Rong Song, Pin Zhao, Jian Min Zhang, Ma Zhong Zhang, Yun Xia Zuo, Jurgen C. de Graaff, Laszlo Vutskits, Peter Szmuk, Charles D. Kurth

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.

Original languageEnglish (US)
Pages (from-to)243-249
Number of pages7
JournalPaediatric anaesthesia
Volume29
Issue number3
DOIs
StatePublished - Mar 2019

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Keywords

  • EEG
  • SAP
  • SAP example
  • SAP template
  • Statistical Analysis Plan
  • isoelectric EEG

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine

Cite this

Yuan, I., Olbrecht, V. A., Mensinger, J. L., Zhang, B., Davidson, A. J., von Ungern-Sternberg, B. S., Skowno, J., Lian, Q. Q., Song, X. R., Zhao, P., Zhang, J. M., Zhang, M. Z., Zuo, Y. X., de Graaff, J. C., Vutskits, L., Szmuk, P., & Kurth, C. D. (2019). Statistical Analysis Plan for “An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery”. Paediatric anaesthesia, 29(3), 243-249. https://doi.org/10.1111/pan.13589