Abstract
A family of transcription factors designated sterol regulatory element-binding proteins (SREBPs) mediates the previously described end-product feedback regulation of cholesterol biosynthesis. In addition, SREBPs are emerging as important regulators of fatty acid synthesis. The current review focuses on the in-vivo regulation of SREBPs in liver and the coordinate regulation of SREBP-activated target genes.
Original language | English (US) |
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Pages (from-to) | 143-150 |
Number of pages | 8 |
Journal | Current opinion in lipidology |
Volume | 10 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1999 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Molecular Biology
- Genetics
- Nutrition and Dietetics
- Cardiology and Cardiovascular Medicine
- Cell Biology