Subversion of Myosin Function by E. coli

Seema Mattoo, Neal M. Alto, Jack E. Dixon

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Enteropathogenic E. coli establish close contact with host cells by nucleating localized actin rearrangements and directly evading phagocytosis. Iizumi et al. now show in a recent issue of Cell Host and Microbe that the type III secretion effector EspB, initially thought to be involved in the translocation of other bacterial effectors, mediates antiphagocytosis and microvilli lesions by inhibiting myosin function.

Original languageEnglish (US)
Pages (from-to)8-10
Number of pages3
JournalDevelopmental Cell
Volume14
Issue number1
DOIs
StatePublished - Jan 15 2008

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ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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