Surgical site infections after colorectal surgery: Do risk factors vary depending on the type of infection considered?

Jennifer Blumetti, Myda Luu, George Sarosi, Kathleen Hartless, Jackie McFarlin, Betty Parker, Sean Dineen, Sergio Huerta, Massimo Asolati, Esteban Varela, Thomas Anthony

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

Background: The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery. Methods: An institutional review board-approved retrospective review was performed examining a 4-year period (January 2002 to December 2005). Patients were included if they had undergone abdominal operations (open or laparoscopic) in which the colon/rectum was surgically manipulated. Patients were excluded if the surgical wound was not closed primarily. A standardized definition of incisional and organ/space infection was employed. Results: A total of 428 operations were performed. Overall, 105 infections were identified (25%); 73 involved the incision and 32 were classified as organ/space. Multivariate analysis suggested that incisional infection was independently associated with body mass index (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.02-1.11) and creation/revision/reversal of an ostomy (OR, 2.2; 95% CI, 1.3-3.9). Organ/space infection was independently associated with perioperative transfusion (OR, 2.3; 95% CI, 1.1-5.5) and with previous abdominal surgery (OR, 2.5; 95% CI, 1.2-5.3). Conclusions: Factors associated with infection differed based on the type of surgical site infection being considered. The lack of overlap between factors associated with incisional infection and organ/space infection suggests that separate risk models and treatment strategies should be developed.

Original languageEnglish (US)
Pages (from-to)704-711
Number of pages8
JournalSurgery
Volume142
Issue number5
DOIs
StatePublished - Nov 2007

Fingerprint

Surgical Wound Infection
Colorectal Surgery
Infection
Odds Ratio
Confidence Intervals
Ostomy
Research Ethics Committees
Rectum
Colon
Body Mass Index
Multivariate Analysis

ASJC Scopus subject areas

  • Surgery

Cite this

Blumetti, J., Luu, M., Sarosi, G., Hartless, K., McFarlin, J., Parker, B., ... Anthony, T. (2007). Surgical site infections after colorectal surgery: Do risk factors vary depending on the type of infection considered? Surgery, 142(5), 704-711. https://doi.org/10.1016/j.surg.2007.05.012

Surgical site infections after colorectal surgery : Do risk factors vary depending on the type of infection considered? / Blumetti, Jennifer; Luu, Myda; Sarosi, George; Hartless, Kathleen; McFarlin, Jackie; Parker, Betty; Dineen, Sean; Huerta, Sergio; Asolati, Massimo; Varela, Esteban; Anthony, Thomas.

In: Surgery, Vol. 142, No. 5, 11.2007, p. 704-711.

Research output: Contribution to journalArticle

Blumetti, J, Luu, M, Sarosi, G, Hartless, K, McFarlin, J, Parker, B, Dineen, S, Huerta, S, Asolati, M, Varela, E & Anthony, T 2007, 'Surgical site infections after colorectal surgery: Do risk factors vary depending on the type of infection considered?', Surgery, vol. 142, no. 5, pp. 704-711. https://doi.org/10.1016/j.surg.2007.05.012
Blumetti, Jennifer ; Luu, Myda ; Sarosi, George ; Hartless, Kathleen ; McFarlin, Jackie ; Parker, Betty ; Dineen, Sean ; Huerta, Sergio ; Asolati, Massimo ; Varela, Esteban ; Anthony, Thomas. / Surgical site infections after colorectal surgery : Do risk factors vary depending on the type of infection considered?. In: Surgery. 2007 ; Vol. 142, No. 5. pp. 704-711.
@article{38e2ca87014042cbb030463e50b297a1,
title = "Surgical site infections after colorectal surgery: Do risk factors vary depending on the type of infection considered?",
abstract = "Background: The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery. Methods: An institutional review board-approved retrospective review was performed examining a 4-year period (January 2002 to December 2005). Patients were included if they had undergone abdominal operations (open or laparoscopic) in which the colon/rectum was surgically manipulated. Patients were excluded if the surgical wound was not closed primarily. A standardized definition of incisional and organ/space infection was employed. Results: A total of 428 operations were performed. Overall, 105 infections were identified (25{\%}); 73 involved the incision and 32 were classified as organ/space. Multivariate analysis suggested that incisional infection was independently associated with body mass index (odds ratio [OR], 1.07; 95{\%} confidence interval [CI], 1.02-1.11) and creation/revision/reversal of an ostomy (OR, 2.2; 95{\%} CI, 1.3-3.9). Organ/space infection was independently associated with perioperative transfusion (OR, 2.3; 95{\%} CI, 1.1-5.5) and with previous abdominal surgery (OR, 2.5; 95{\%} CI, 1.2-5.3). Conclusions: Factors associated with infection differed based on the type of surgical site infection being considered. The lack of overlap between factors associated with incisional infection and organ/space infection suggests that separate risk models and treatment strategies should be developed.",
author = "Jennifer Blumetti and Myda Luu and George Sarosi and Kathleen Hartless and Jackie McFarlin and Betty Parker and Sean Dineen and Sergio Huerta and Massimo Asolati and Esteban Varela and Thomas Anthony",
year = "2007",
month = "11",
doi = "10.1016/j.surg.2007.05.012",
language = "English (US)",
volume = "142",
pages = "704--711",
journal = "Surgery (United States)",
issn = "0039-6060",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - Surgical site infections after colorectal surgery

T2 - Do risk factors vary depending on the type of infection considered?

AU - Blumetti, Jennifer

AU - Luu, Myda

AU - Sarosi, George

AU - Hartless, Kathleen

AU - McFarlin, Jackie

AU - Parker, Betty

AU - Dineen, Sean

AU - Huerta, Sergio

AU - Asolati, Massimo

AU - Varela, Esteban

AU - Anthony, Thomas

PY - 2007/11

Y1 - 2007/11

N2 - Background: The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery. Methods: An institutional review board-approved retrospective review was performed examining a 4-year period (January 2002 to December 2005). Patients were included if they had undergone abdominal operations (open or laparoscopic) in which the colon/rectum was surgically manipulated. Patients were excluded if the surgical wound was not closed primarily. A standardized definition of incisional and organ/space infection was employed. Results: A total of 428 operations were performed. Overall, 105 infections were identified (25%); 73 involved the incision and 32 were classified as organ/space. Multivariate analysis suggested that incisional infection was independently associated with body mass index (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.02-1.11) and creation/revision/reversal of an ostomy (OR, 2.2; 95% CI, 1.3-3.9). Organ/space infection was independently associated with perioperative transfusion (OR, 2.3; 95% CI, 1.1-5.5) and with previous abdominal surgery (OR, 2.5; 95% CI, 1.2-5.3). Conclusions: Factors associated with infection differed based on the type of surgical site infection being considered. The lack of overlap between factors associated with incisional infection and organ/space infection suggests that separate risk models and treatment strategies should be developed.

AB - Background: The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery. Methods: An institutional review board-approved retrospective review was performed examining a 4-year period (January 2002 to December 2005). Patients were included if they had undergone abdominal operations (open or laparoscopic) in which the colon/rectum was surgically manipulated. Patients were excluded if the surgical wound was not closed primarily. A standardized definition of incisional and organ/space infection was employed. Results: A total of 428 operations were performed. Overall, 105 infections were identified (25%); 73 involved the incision and 32 were classified as organ/space. Multivariate analysis suggested that incisional infection was independently associated with body mass index (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.02-1.11) and creation/revision/reversal of an ostomy (OR, 2.2; 95% CI, 1.3-3.9). Organ/space infection was independently associated with perioperative transfusion (OR, 2.3; 95% CI, 1.1-5.5) and with previous abdominal surgery (OR, 2.5; 95% CI, 1.2-5.3). Conclusions: Factors associated with infection differed based on the type of surgical site infection being considered. The lack of overlap between factors associated with incisional infection and organ/space infection suggests that separate risk models and treatment strategies should be developed.

UR - http://www.scopus.com/inward/record.url?scp=35548994897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35548994897&partnerID=8YFLogxK

U2 - 10.1016/j.surg.2007.05.012

DO - 10.1016/j.surg.2007.05.012

M3 - Article

C2 - 17981191

AN - SCOPUS:35548994897

VL - 142

SP - 704

EP - 711

JO - Surgery (United States)

JF - Surgery (United States)

SN - 0039-6060

IS - 5

ER -