Telomerase: A target for cancer therapeutics

Jerry W. Shay, Woodring E. Wright

Research output: Contribution to journalReview article

284 Scopus citations

Abstract

The continuous growth of advanced malignancies almost universally correlates with the reactivation of telomerase. While there is still a great deal of basic and applied research to be done, telomerase remains a very attractive novel target for cancer therapeutics. In this review, we will discuss the challenges and the pros and cons of the most promising antitelomerase approaches currently being investigated.

Original languageEnglish (US)
Pages (from-to)257-265
Number of pages9
JournalCancer Cell
Volume2
Issue number4
DOIs
StatePublished - Oct 2002

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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