Telomerase: A target for cancer therapeutics

Jerry W. Shay, Woodring E. Wright

Research output: Contribution to journalArticle

276 Citations (Scopus)

Abstract

The continuous growth of advanced malignancies almost universally correlates with the reactivation of telomerase. While there is still a great deal of basic and applied research to be done, telomerase remains a very attractive novel target for cancer therapeutics. In this review, we will discuss the challenges and the pros and cons of the most promising antitelomerase approaches currently being investigated.

Original languageEnglish (US)
Pages (from-to)257-265
Number of pages9
JournalCancer Cell
Volume2
Issue number4
DOIs
StatePublished - Oct 2002

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Telomerase
Neoplasms
Therapeutics
Growth
Research

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Oncology

Cite this

Telomerase : A target for cancer therapeutics. / Shay, Jerry W.; Wright, Woodring E.

In: Cancer Cell, Vol. 2, No. 4, 10.2002, p. 257-265.

Research output: Contribution to journalArticle

Shay, Jerry W. ; Wright, Woodring E. / Telomerase : A target for cancer therapeutics. In: Cancer Cell. 2002 ; Vol. 2, No. 4. pp. 257-265.
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