Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary, Dongguang Qin, Donna McEachern, Meilan Liu, Rebecca S. Miller, Su Qiu, Zaneta Nikolovska-Coleska, Ke Ding, Guoping Wang, Jianyong Chen, Denzil Bernard, Jian Zhang, Yipin Lu, Qingyang Gu, Rajal B. Shah, Kenneth J. Pienta, Xiaolan Ling, Sanmao Kang, Ming Guo, Yi SunDajun Yang, Shaomeng Wang

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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

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Medicine & Life Sciences