Texture analysis of magnetic resonance images of the human placenta throughout gestation: A feasibility study

Quyen N. Do, Matthew A Lewis, Ananth J Madhuranthakam, Yin Xi, April A Bailey, Robert E Lenkinski, Diane M Twickler

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

As fetal gestational age increases, other modalities such as ultrasound have demonstrated increased levels of heterogeneity in the normal placenta. In this study, we introduce and apply ROI-based texture analysis to a retrospective fetal MRI database to characterize the second-order statistics of placenta and to evaluate the relationship between heterogeneity and gestational age. Positive correlations were observed for several Haralick texture metrics derived from fetal-brain specific T2-weighted and gravid uterus T1-weighted and T2-weighted images, confirming a quantitative increase in placental heterogeneity with gestational age. Our study shows the importance of identifying baseline MR textural changes at certain gestational ages from which placental diseased states may be compared. Specifically, when evaluating for placental invasion or insufficiency, findings should be evaluated in the context of the normal placental aging process, which occurs throughout gestation.

Original languageEnglish (US)
Article numbere0211060
JournalPLoS One
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2019

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gestational age
Feasibility Studies
Magnetic resonance
placenta
Placenta
Gestational Age
Magnetic Resonance Spectroscopy
Textures
texture
pregnancy
Pregnancy
Magnetic resonance imaging
Brain
Aging of materials
Ultrasonics
Statistics
Placenta Diseases
uterus
Uterus
statistics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Texture analysis of magnetic resonance images of the human placenta throughout gestation : A feasibility study. / Do, Quyen N.; Lewis, Matthew A; Madhuranthakam, Ananth J; Xi, Yin; Bailey, April A; Lenkinski, Robert E; Twickler, Diane M.

In: PLoS One, Vol. 14, No. 1, e0211060, 01.01.2019.

Research output: Contribution to journalArticle

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