The berlin heart EXCOR pediatric ventricular assist device: History, north american experience, and future directions

Charles D. Fraser, Robert D B Jaquiss

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Options for long-term mechanical circulatory support to sustain pediatric heart failure patients requiring cardiac transplantation while they wait for donor hearts have been unsatisfactory. The conventional approach has been to use extracorporeal membrane oxygenation (ECMO), but its lack of feasibility for long-term use and the major complications associated with the technology have limited its use, especially in light of lengthy waiting lists for donor hearts. With the advent of the Berlin Heart EXCOR® Pediatric ventricular assist device (VAD), pediatric heart failure specialists have gained an important tool for helping this patient population survive until a donor heart can be identified. The EXCOR Pediatric VAD is designed to support pediatric patients of all age groups, from newborns to teenagers, and can be used successfully for many months. This paper describes the early experience with the EXCOR Pediatric VAD and the challenging journey undertaken to gain U.S. FDA approval, including successful completion of the first worldwide prospective clinical study of VADs in a pediatric population

Original languageEnglish (US)
Pages (from-to)96-105
Number of pages10
JournalAnnals of the New York Academy of Sciences
Volume1291
Issue number1
DOIs
StatePublished - Jul 1 2013

Fingerprint

Pediatrics
Heart-Assist Devices
Berlin
History
Tissue Donors
Heart Failure
Extracorporeal Membrane Oxygenation
Oxygenation
Waiting Lists
Heart Transplantation
Direction compound
Population
Age Groups
Newborn Infant
Prospective Studies
Technology
Membranes

Keywords

  • Berlin Heart
  • EXCOR
  • Pediatrics
  • VAD

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

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