TY - JOUR
T1 - The Biology and Clinical Features of Cutaneous Polyomaviruses
AU - Nguyen, Khang Duy
AU - Chamseddin, Bahir H.
AU - Cockerell, Clay J
AU - Wang, Richard C
N1 - Funding Information:
We thank the Wang laboratory for helpful discussions and Peter Pavlidakey for the histologic images of HPyV7 infection. RW is supported by a National Institute of Arthritis and Musculoskeletal and Skin Diseases 1R01AR072655 , a Burroughs Wellcome Fund Career Award for Medical Scientists (1010978), and American Cancer Society Research Scholar Award (RSG-18-058-01).
Publisher Copyright:
© 2018 The Authors
PY - 2019/2
Y1 - 2019/2
N2 - Human polyomaviruses are double-stand DNA viruses with a conserved genomic structure, yet they present with diverse tissue tropisms and disease presentations. Merkel cell polyomavirus, trichodysplasia spinulosa polyomavirus, human polyomavirus 6 and 7, and Malawi polyomavirus are shed from the skin, and Merkel cell polyomavirus, trichodysplasia spinulosa polyomavirus, human polyomavirus 6 and 7 have been linked to specific skin diseases. We present an update on the genomic and clinical features of these cutaneous polyomaviruses.
AB - Human polyomaviruses are double-stand DNA viruses with a conserved genomic structure, yet they present with diverse tissue tropisms and disease presentations. Merkel cell polyomavirus, trichodysplasia spinulosa polyomavirus, human polyomavirus 6 and 7, and Malawi polyomavirus are shed from the skin, and Merkel cell polyomavirus, trichodysplasia spinulosa polyomavirus, human polyomavirus 6 and 7 have been linked to specific skin diseases. We present an update on the genomic and clinical features of these cutaneous polyomaviruses.
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U2 - 10.1016/j.jid.2018.09.013
DO - 10.1016/j.jid.2018.09.013
M3 - Review article
C2 - 30470393
AN - SCOPUS:85056854254
SN - 0022-202X
VL - 139
SP - 285
EP - 292
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
IS - 2
ER -