The diverse bacterial origins of the Arabidopsis polyamine biosynthetic pathway

Crista Illingworth, Melinda J. Mayer, Katherine Elliott, Colin Hanfrey, Nicholas J. Walton, Anthony J. Michael

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

We functionally identified the last remaining step in the plant polyamine biosynthetic pathway by expressing an Arabidopsis thaliana agmatine iminohydrolase cDNA in yeast. Inspection of the whole pathway suggests that the arginine decarboxylase, agmatine iminohydrolase, N-carbamoylputrescine amidohydrolase route to putrescine in plants was inherited from the cyanobacterial ancestor of the chloroplast. However, the rest of the pathway including ornithine decarboxylase and spermidine synthase was probably inherited from bacterial genes present in the original host cell, common ancestor of plants and animals, that acquired the cyanobacterial endosymbiont. An exception is S-adenosylmethionine decarboxylase, which may represent a eukaryote-specific enzyme form.

Original languageEnglish (US)
Pages (from-to)26-30
Number of pages5
JournalFEBS Letters
Volume549
Issue number1-3
DOIs
StatePublished - Aug 14 2003

Fingerprint

agmatine deiminase
Biosynthetic Pathways
Polyamines
Arabidopsis
Spermidine Synthase
Adenosylmethionine Decarboxylase
Amidohydrolases
Ornithine Decarboxylase
Putrescine
Yeast
Bacterial Genes
Animals
Complementary DNA
Genes
Inspection
Chloroplasts
Eukaryota
Enzymes
Yeasts

Keywords

  • Agmatine iminohydrolase
  • Arabidopsis
  • Chloroplast targeting sequence
  • Cyanobacteria
  • Polyamine

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

The diverse bacterial origins of the Arabidopsis polyamine biosynthetic pathway. / Illingworth, Crista; Mayer, Melinda J.; Elliott, Katherine; Hanfrey, Colin; Walton, Nicholas J.; Michael, Anthony J.

In: FEBS Letters, Vol. 549, No. 1-3, 14.08.2003, p. 26-30.

Research output: Contribution to journalArticle

Illingworth, C, Mayer, MJ, Elliott, K, Hanfrey, C, Walton, NJ & Michael, AJ 2003, 'The diverse bacterial origins of the Arabidopsis polyamine biosynthetic pathway', FEBS Letters, vol. 549, no. 1-3, pp. 26-30. https://doi.org/10.1016/S0014-5793(03)00756-7
Illingworth, Crista ; Mayer, Melinda J. ; Elliott, Katherine ; Hanfrey, Colin ; Walton, Nicholas J. ; Michael, Anthony J. / The diverse bacterial origins of the Arabidopsis polyamine biosynthetic pathway. In: FEBS Letters. 2003 ; Vol. 549, No. 1-3. pp. 26-30.
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