The effect of polypeptide hormones on lipid monolayers. III. The effect of insulin, vasopressin, oxytocin, albumin, and prostaglandin E1 on the specific resistance to the evaporation of water through monomolecular films of monoöctadecyl phosphate, stearic acid, and stearyl alcohol

Marian S. Kafka, Charles Y C Pak

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The hypothesis that insulin and vasopressin increase the permeability of cells to water and water-soluble substances by decreasing the adsorption of Ca2+ at the outer surface of the plasma membrane was tested in a model system. Changes in the specific resistance to the evaporation of water through monoöctadecyl phosphate (mOP) monolayers were compared with simultaneous changes in Ca2+ adsorption. Insulin and vasopressin cause a decrease in the resistance (or, alternatively, increase the transport of water) which can be accounted for only in part by the inhibition of Ca2+ adsorption. The action is specific for these hormones and dependent on interaction between the hormone and monolayer molecules.

Original languageEnglish (US)
Pages (from-to)148-155
Number of pages8
JournalJournal of Colloid And Interface Science
Volume41
Issue number1
DOIs
StatePublished - Oct 1972

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry

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