The impact of percutaneous coronary intervention of chronic total occlusions on left ventricular function and clinical outcomes

Georgios E. Christakopoulos, Muhammad Nauman J Tarar, Emmanouil S. Brilakis

Research output: Contribution to journalArticle

4 Scopus citations


A meta-analysis by Hoebers et al. reported that successful chronic total occlusion (CTO) recanalization resulted in an increase in left ventricular (LV) ejection fraction by 4.44% (P < 0.01) and a reduction in LV end-diastolic volume by 6.14 mL/m<sup>2</sup> during follow-up as compared with baseline, suggesting beneficial LV remodeling. These findings are important as the myocardium supplied by a CTO frequently has sustained irreversible injury and further support the clinical benefits of CTO interventions.

Original languageEnglish (US)
Pages (from-to)1107-1110
Number of pages4
JournalJournal of Thoracic Disease
Issue number7
Publication statusPublished - 2015



  • Chronic total occlusion (CTO)
  • Left ventricle
  • Outcomes
  • Percutaneous coronary intervention (PCI)

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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