The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Jon S. Blevins, Andrew T. Revel, Melissa J. Caimano, Xiaofeng F. Yang, James A. Richardson, Kayla E. Hagman, Michael V. Norgard

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

Original languageEnglish (US)
Pages (from-to)4864-4867
Number of pages4
JournalInfection and Immunity
Volume72
Issue number8
DOIs
StatePublished - Aug 2004

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Borrelia burgdorferi
Ticks
Molting
Nymph
Ixodes
Arthropods
Genes
Larva

ASJC Scopus subject areas

  • Immunology

Cite this

The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease. / Blevins, Jon S.; Revel, Andrew T.; Caimano, Melissa J.; Yang, Xiaofeng F.; Richardson, James A.; Hagman, Kayla E.; Norgard, Michael V.

In: Infection and Immunity, Vol. 72, No. 8, 08.2004, p. 4864-4867.

Research output: Contribution to journalArticle

Blevins, Jon S. ; Revel, Andrew T. ; Caimano, Melissa J. ; Yang, Xiaofeng F. ; Richardson, James A. ; Hagman, Kayla E. ; Norgard, Michael V. / The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease. In: Infection and Immunity. 2004 ; Vol. 72, No. 8. pp. 4864-4867.
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