The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Jon S. Blevins, Andrew T. Revel, Melissa J. Caimano, Xiaofeng F. Yang, James A. Richardson, Kayla E. Hagman, Michael V. Norgard

Research output: Contribution to journalArticle

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luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

Original languageEnglish (US)
Pages (from-to)4864-4867
Number of pages4
JournalInfection and immunity
Issue number8
StatePublished - Aug 1 2004


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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