The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Jon S. Blevins, Andrew T. Revel, Melissa J. Caimano, Xiaofeng F. Yang, James A. Richardson, Kayla E. Hagman, Michael V. Norgard

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

Original languageEnglish (US)
Pages (from-to)4864-4867
Number of pages4
JournalInfection and immunity
Volume72
Issue number8
DOIs
StatePublished - Aug 1 2004

    Fingerprint

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this