The rate of warping in irradiated and nonirradiated homograft rib cartilage

A controlled comparison and clinical implications

William P. Adams, Rod J. Rohrich, Jack P. Gunter, Cliff P. Clark, Jack B. Robinson

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Irradiated homograft costal cartilage reportedly warps less than autologous cartilage based on clinical observation; however, no controlled, experimental studies on the warping characteristics of irradiated homograft costal cartilage have been done. Fresh cadaver costal cartilage (ribs 5 through 8) was prepared and irradiated using a standardized technique. A specially designed cartilage-cutting device was used to cut the cartilage into a reproducible size. The irradiated (n = 23) and nonirradiated (n = 20) groups were incubated in vitro and assessed over a 4-week period. There was no significant difference in warping between the irradiated and nonirradiated groups (p = 0.1). The centrally cut pieces of cartilage in each group warped less than peripherally cut blocks in each group. Peripherally cut pieces of both the irradiated and nonirradiated groups warped at a faster rate compared with the nonirradiated groups. All cartilage exhibited continued warping over the 4-week study period. We concluded that there was no difference in warping characteristics between irradiated and nonirradiated homograft rib cartilage. Furthermore, unlike previous studies, cartilage grafts continued warping over time for at least 4 weeks, and this phenomenon may be extrapolated as a causative factor in delayed postoperative nasal deviation after rhinoplasty and nasal reconstruction where rib grafts are used.

Original languageEnglish (US)
Pages (from-to)265-270
Number of pages6
JournalPlastic and Reconstructive Surgery
Volume103
Issue number1
StatePublished - 1999

Fingerprint

Ribs
Cartilage
Allografts
Nose
Transplants
Rhinoplasty
Cadaver
Observation
Equipment and Supplies
Costal Cartilage

ASJC Scopus subject areas

  • Surgery

Cite this

The rate of warping in irradiated and nonirradiated homograft rib cartilage : A controlled comparison and clinical implications. / Adams, William P.; Rohrich, Rod J.; Gunter, Jack P.; Clark, Cliff P.; Robinson, Jack B.

In: Plastic and Reconstructive Surgery, Vol. 103, No. 1, 1999, p. 265-270.

Research output: Contribution to journalArticle

Adams, William P. ; Rohrich, Rod J. ; Gunter, Jack P. ; Clark, Cliff P. ; Robinson, Jack B. / The rate of warping in irradiated and nonirradiated homograft rib cartilage : A controlled comparison and clinical implications. In: Plastic and Reconstructive Surgery. 1999 ; Vol. 103, No. 1. pp. 265-270.
@article{8a9dc136e6b54b37b700e8185b041a5c,
title = "The rate of warping in irradiated and nonirradiated homograft rib cartilage: A controlled comparison and clinical implications",
abstract = "Irradiated homograft costal cartilage reportedly warps less than autologous cartilage based on clinical observation; however, no controlled, experimental studies on the warping characteristics of irradiated homograft costal cartilage have been done. Fresh cadaver costal cartilage (ribs 5 through 8) was prepared and irradiated using a standardized technique. A specially designed cartilage-cutting device was used to cut the cartilage into a reproducible size. The irradiated (n = 23) and nonirradiated (n = 20) groups were incubated in vitro and assessed over a 4-week period. There was no significant difference in warping between the irradiated and nonirradiated groups (p = 0.1). The centrally cut pieces of cartilage in each group warped less than peripherally cut blocks in each group. Peripherally cut pieces of both the irradiated and nonirradiated groups warped at a faster rate compared with the nonirradiated groups. All cartilage exhibited continued warping over the 4-week study period. We concluded that there was no difference in warping characteristics between irradiated and nonirradiated homograft rib cartilage. Furthermore, unlike previous studies, cartilage grafts continued warping over time for at least 4 weeks, and this phenomenon may be extrapolated as a causative factor in delayed postoperative nasal deviation after rhinoplasty and nasal reconstruction where rib grafts are used.",
author = "Adams, {William P.} and Rohrich, {Rod J.} and Gunter, {Jack P.} and Clark, {Cliff P.} and Robinson, {Jack B.}",
year = "1999",
language = "English (US)",
volume = "103",
pages = "265--270",
journal = "Plastic and Reconstructive Surgery",
issn = "0032-1052",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - The rate of warping in irradiated and nonirradiated homograft rib cartilage

T2 - A controlled comparison and clinical implications

AU - Adams, William P.

AU - Rohrich, Rod J.

AU - Gunter, Jack P.

AU - Clark, Cliff P.

AU - Robinson, Jack B.

PY - 1999

Y1 - 1999

N2 - Irradiated homograft costal cartilage reportedly warps less than autologous cartilage based on clinical observation; however, no controlled, experimental studies on the warping characteristics of irradiated homograft costal cartilage have been done. Fresh cadaver costal cartilage (ribs 5 through 8) was prepared and irradiated using a standardized technique. A specially designed cartilage-cutting device was used to cut the cartilage into a reproducible size. The irradiated (n = 23) and nonirradiated (n = 20) groups were incubated in vitro and assessed over a 4-week period. There was no significant difference in warping between the irradiated and nonirradiated groups (p = 0.1). The centrally cut pieces of cartilage in each group warped less than peripherally cut blocks in each group. Peripherally cut pieces of both the irradiated and nonirradiated groups warped at a faster rate compared with the nonirradiated groups. All cartilage exhibited continued warping over the 4-week study period. We concluded that there was no difference in warping characteristics between irradiated and nonirradiated homograft rib cartilage. Furthermore, unlike previous studies, cartilage grafts continued warping over time for at least 4 weeks, and this phenomenon may be extrapolated as a causative factor in delayed postoperative nasal deviation after rhinoplasty and nasal reconstruction where rib grafts are used.

AB - Irradiated homograft costal cartilage reportedly warps less than autologous cartilage based on clinical observation; however, no controlled, experimental studies on the warping characteristics of irradiated homograft costal cartilage have been done. Fresh cadaver costal cartilage (ribs 5 through 8) was prepared and irradiated using a standardized technique. A specially designed cartilage-cutting device was used to cut the cartilage into a reproducible size. The irradiated (n = 23) and nonirradiated (n = 20) groups were incubated in vitro and assessed over a 4-week period. There was no significant difference in warping between the irradiated and nonirradiated groups (p = 0.1). The centrally cut pieces of cartilage in each group warped less than peripherally cut blocks in each group. Peripherally cut pieces of both the irradiated and nonirradiated groups warped at a faster rate compared with the nonirradiated groups. All cartilage exhibited continued warping over the 4-week study period. We concluded that there was no difference in warping characteristics between irradiated and nonirradiated homograft rib cartilage. Furthermore, unlike previous studies, cartilage grafts continued warping over time for at least 4 weeks, and this phenomenon may be extrapolated as a causative factor in delayed postoperative nasal deviation after rhinoplasty and nasal reconstruction where rib grafts are used.

UR - http://www.scopus.com/inward/record.url?scp=0032607594&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032607594&partnerID=8YFLogxK

M3 - Article

VL - 103

SP - 265

EP - 270

JO - Plastic and Reconstructive Surgery

JF - Plastic and Reconstructive Surgery

SN - 0032-1052

IS - 1

ER -