TY - JOUR
T1 - The skin in disseminated intravascular coagulation
T2 - PROSPECTIVE ANALYSIS OF THIRTY‐SIX CASES
AU - Robboy, S. J.
AU - Mihm, M. C.
AU - Colman, R. W.
AU - Minna, J. D.
PY - 1973/3
Y1 - 1973/3
N2 - The cutaneous manifestations of disseminated intravascular coagulation (DIC) present in thirty‐three of forty‐five patients included petechiae, purpura, palpable variants of both, acral cyanosis, haemorrhagic bullae, purpura fulminans, subcutaneous dissecting haematomata, or bleeding from wound or venipuncture sites. In 47% of cases cutaneous lesions were the presenting sign. Coagulation tests were usually abnormal in a pattern diagnostic of DIC. However when initial coagulation‐test observations were equivocal, punch biopsy of the skin yielded fibrin thrombi and thus was helpful in the early diagnosis of DIC, later confirmed by serial coagulation studies. Recognition of the types of skin lesions associated with DIC permits prompt diagnosis and institution of appropriate therapy.
AB - The cutaneous manifestations of disseminated intravascular coagulation (DIC) present in thirty‐three of forty‐five patients included petechiae, purpura, palpable variants of both, acral cyanosis, haemorrhagic bullae, purpura fulminans, subcutaneous dissecting haematomata, or bleeding from wound or venipuncture sites. In 47% of cases cutaneous lesions were the presenting sign. Coagulation tests were usually abnormal in a pattern diagnostic of DIC. However when initial coagulation‐test observations were equivocal, punch biopsy of the skin yielded fibrin thrombi and thus was helpful in the early diagnosis of DIC, later confirmed by serial coagulation studies. Recognition of the types of skin lesions associated with DIC permits prompt diagnosis and institution of appropriate therapy.
UR - http://www.scopus.com/inward/record.url?scp=0015907945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015907945&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2133.1973.tb07538.x
DO - 10.1111/j.1365-2133.1973.tb07538.x
M3 - Article
C2 - 4197291
AN - SCOPUS:0015907945
SN - 0007-0963
VL - 88
SP - 221
EP - 229
JO - British Journal of Dermatology
JF - British Journal of Dermatology
IS - 3
ER -