The skin in disseminated intravascular coagulation

prospective analysis of thirty six cases

S. J. Robboy, M. C. Mihm, R. W. Colman, J. D. Minna

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

The cutaneous manifestations of disseminated intravascular coagulation (DIC) present in 33 of 45 patients included petechiae, purpura, palpable variants of both, acral cyanosis, hemorrhagic bullae, purpura fulminans, subcutaneous dissecting hematomata, or bleeding from wound or venipuncture sites. In 47% of cases, cutaneous lesions were the presenting sign. Coagulation tests were usually abnormal in a pattern diagnostic of DIC. However when initial coagulation test observations were equivocal, punch biopsy of the skin yielded fibrin thrombi and thus was helpful in the early diagnosis of DIC, later confirmed by serial coagulation studies. Recognition of the types of skin lesions associated with DIC permits prompt diagnosis and institution of appropriate therapy.

Original languageEnglish (US)
Pages (from-to)221-229
Number of pages9
JournalBritish Journal of Dermatology
Volume88
Issue number3
StatePublished - 1973

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Disseminated Intravascular Coagulation
Skin
Purpura
Purpura Fulminans
Skin Manifestations
Cyanosis
Phlebotomy
Blister
Fibrin
Hematoma
Early Diagnosis
Thrombosis
Extremities
Hemorrhage
Biopsy
Wounds and Injuries
Therapeutics

ASJC Scopus subject areas

  • Dermatology

Cite this

The skin in disseminated intravascular coagulation : prospective analysis of thirty six cases. / Robboy, S. J.; Mihm, M. C.; Colman, R. W.; Minna, J. D.

In: British Journal of Dermatology, Vol. 88, No. 3, 1973, p. 221-229.

Research output: Contribution to journalArticle

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