The treatment of osteoporosis with calcium infusions. Evaluation of bone biopsies

Jenifer Jowsey, Robert C. Hoye, Charles Y C Pak, Frederic C. Bartter

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Repeated infusions of calcium gluconate were given to six men with idiopathic osteoporosis; bone morphology was studied by microradiography. In three patients the relative surface area of bone showing the pattern of new bone formation was initially low; in all, it returned to the normal range with the infusions. In four patients the relative area showing resorption was initially high; in all, it returned to normal with the infusions. The results are interpreted to support the suggestion that idiopathic osteoporosis results from imbalance between parathyroid hormone (PTH) secretion and thyrocalcitonin (TCT) secretion and that calcium (Ca) infusion suppresses the former and stimulates the latter.

Original languageEnglish (US)
Pages (from-to)17-22
Number of pages6
JournalThe American journal of medicine
Volume47
Issue number1
StatePublished - Jul 1969

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Osteoporosis
Microradiography
Calcium Gluconate
Calcium
Biopsy
Bone and Bones
Calcitonin
Parathyroid Hormone
Osteogenesis
Reference Values
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

The treatment of osteoporosis with calcium infusions. Evaluation of bone biopsies. / Jowsey, Jenifer; Hoye, Robert C.; Pak, Charles Y C; Bartter, Frederic C.

In: The American journal of medicine, Vol. 47, No. 1, 07.1969, p. 17-22.

Research output: Contribution to journalArticle

Jowsey, Jenifer ; Hoye, Robert C. ; Pak, Charles Y C ; Bartter, Frederic C. / The treatment of osteoporosis with calcium infusions. Evaluation of bone biopsies. In: The American journal of medicine. 1969 ; Vol. 47, No. 1. pp. 17-22.
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