The yeast metabolic cycle

Insights into the life of a eukaryotic cell

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The budding yeast Saccharomyces cerevisiae undergoes robust oscillations in oxygen consumption during continuous growth under nutrient-limited conditions. Comprehensive microarray studies reveal that more than half of the yeast genome is expressed periodically as a function of these respiratory oscillations, thereby specifying an extensively orchestrated program responsible for regulating numerous cellular outputs. Here, we summarize the logic of the yeast metabolic cycle (YMC) and highlight additional cellular processes that are predicted to be compartmentalized in time. Certain principles of temporal orchestration as seen during the YMC might be conserved across other biological cycles.

Original languageEnglish (US)
Pages (from-to)339-343
Number of pages5
JournalCold Spring Harbor Symposia on Quantitative Biology
Volume72
DOIs
StatePublished - 2007

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Eukaryotic Cells
Yeast
eukaryotic cells
Yeasts
yeasts
oscillation
Saccharomycetales
Oxygen Consumption
Saccharomyces cerevisiae
lung function
Genome
oxygen consumption
Food
Microarrays
Nutrients
Growth
Genes
genome
Oxygen
nutrients

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Biochemistry
  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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