Therapeutic plasma exchange in the immune hemolytic anemias and immunologic thrombocytopenic purpura.

B. D. Brooks, E. A. Steane, R. G. Sheehan, E. P. Frenkel

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Thus, plasma exchange appears to have a potential but limited role in the care of antibody mediated injury of red cells or platelets. Its clearest indication appears to be in those uncommon instances of warm antibody mediated hemolysis with a highly fulminant course where the classical therapeutic measures do not have adequate time for effect. Similarly, such therapy appears to have significant potential in cases of acute immunologic thrombocytopenic purpura where some clinical contraindication to steroids, immunosuppressive agents or splenectomy exists. Acute ITP of pregnancy may provide another important setting for such a therapeutic approach. Finally, plasma exchange has been shown to provide temporary clinical stability in cases of chronic cold agglutinin disease.

Original languageEnglish (US)
Pages (from-to)317-329
Number of pages13
JournalProgress in Clinical and Biological Research
Volume106
StatePublished - 1982

Fingerprint

Thrombocytopenic Purpura
Plasma Exchange
Hemolytic Anemia
Inosine Triphosphate
Autoimmune Hemolytic Anemia
Antibodies
Splenectomy
Immunosuppressive Agents
Hemolysis
Therapeutics
Blood Platelets
Steroids
Pregnancy
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Therapeutic plasma exchange in the immune hemolytic anemias and immunologic thrombocytopenic purpura. / Brooks, B. D.; Steane, E. A.; Sheehan, R. G.; Frenkel, E. P.

In: Progress in Clinical and Biological Research, Vol. 106, 1982, p. 317-329.

Research output: Contribution to journalArticle

@article{0892c6e253ef48d7915d7a6833644d20,
title = "Therapeutic plasma exchange in the immune hemolytic anemias and immunologic thrombocytopenic purpura.",
abstract = "Thus, plasma exchange appears to have a potential but limited role in the care of antibody mediated injury of red cells or platelets. Its clearest indication appears to be in those uncommon instances of warm antibody mediated hemolysis with a highly fulminant course where the classical therapeutic measures do not have adequate time for effect. Similarly, such therapy appears to have significant potential in cases of acute immunologic thrombocytopenic purpura where some clinical contraindication to steroids, immunosuppressive agents or splenectomy exists. Acute ITP of pregnancy may provide another important setting for such a therapeutic approach. Finally, plasma exchange has been shown to provide temporary clinical stability in cases of chronic cold agglutinin disease.",
author = "Brooks, {B. D.} and Steane, {E. A.} and Sheehan, {R. G.} and Frenkel, {E. P.}",
year = "1982",
language = "English (US)",
volume = "106",
pages = "317--329",
journal = "Progress in Clinical and Biological Research",
issn = "0361-7742",
publisher = "John Wiley and Sons Inc.",

}

TY - JOUR

T1 - Therapeutic plasma exchange in the immune hemolytic anemias and immunologic thrombocytopenic purpura.

AU - Brooks, B. D.

AU - Steane, E. A.

AU - Sheehan, R. G.

AU - Frenkel, E. P.

PY - 1982

Y1 - 1982

N2 - Thus, plasma exchange appears to have a potential but limited role in the care of antibody mediated injury of red cells or platelets. Its clearest indication appears to be in those uncommon instances of warm antibody mediated hemolysis with a highly fulminant course where the classical therapeutic measures do not have adequate time for effect. Similarly, such therapy appears to have significant potential in cases of acute immunologic thrombocytopenic purpura where some clinical contraindication to steroids, immunosuppressive agents or splenectomy exists. Acute ITP of pregnancy may provide another important setting for such a therapeutic approach. Finally, plasma exchange has been shown to provide temporary clinical stability in cases of chronic cold agglutinin disease.

AB - Thus, plasma exchange appears to have a potential but limited role in the care of antibody mediated injury of red cells or platelets. Its clearest indication appears to be in those uncommon instances of warm antibody mediated hemolysis with a highly fulminant course where the classical therapeutic measures do not have adequate time for effect. Similarly, such therapy appears to have significant potential in cases of acute immunologic thrombocytopenic purpura where some clinical contraindication to steroids, immunosuppressive agents or splenectomy exists. Acute ITP of pregnancy may provide another important setting for such a therapeutic approach. Finally, plasma exchange has been shown to provide temporary clinical stability in cases of chronic cold agglutinin disease.

UR - http://www.scopus.com/inward/record.url?scp=0020433616&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020433616&partnerID=8YFLogxK

M3 - Article

VL - 106

SP - 317

EP - 329

JO - Progress in Clinical and Biological Research

JF - Progress in Clinical and Biological Research

SN - 0361-7742

ER -