Abstract
Corona virus 2 (SARS-CoV2/ Severe Acute Respiratory Syndrome Corona Virus 2) infection has emerged as a global health crisis. Incidence of thromboembolic disease is reported to be high in SARS-CoV2 disease and is seen in a multitude of organ systems ranging from cutaneous thrombosis to pulmonary embolism, stroke or coronary thrombosis sometimes with catastrophic outcomes. Evidence points towards a key role of thromboembolism, hypercoagulability and over production of proinflammatory cytokines mimicking a "cytokine storm"which leads to multiorgan failure. This brief narrative review highlights the pathophysiology and risk factors of thromboembolic disease and provides a framework for management of anticoagulation based on the current evidence.
Original language | English (US) |
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Article number | 70 |
Journal | Journal of Intensive Care |
Volume | 8 |
Issue number | 1 |
DOIs | |
State | Published - Sep 14 2020 |
Externally published | Yes |
Keywords
- COVID-19
- SARS-CoV2
- coagulation
- management
- thromboembolism
- thrombosis
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine