Toll we meet again

Bruce Beutler, Alexander Poltorak

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations


Remodeling of chromatin, distinct from activation of NF-κB, is a newly identified function of Toll-like receptors in mammals. In Drosophila, Toll receptors play a role in development as well as immunity; yet in mammals, they have an immunological role only. Further clues to the evolutionary development of the Toll receptors are emerging.

Original languageEnglish (US)
Pages (from-to)9-10
Number of pages2
JournalNature Immunology
Issue number1
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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