TY - JOUR
T1 - Total synthesis of 5(S),20- and 15(S),20-dihydroxyeicosatetraenoic acid and 5(S),6(R)-epoxy-20-hydroxy- and 14(R),15(S)-epoxy-20-hydroxyeicosatreinoic acid
AU - Lumin, Sun
AU - Yadagiri, Pendri
AU - Falck, J R
AU - Capdevila, Jorge
AU - Mosset, Paul
AU - Grée, René
PY - 1987/12/1
Y1 - 1987/12/1
N2 - Aldehyde (1), derived from dimethyl L-malate, was exploited in a stereocontrolled total synthesis of the ω-hydroxylated eicosanoid metabolites 5(S),20- and 15(S),20-dihydroxyeicosatetraenoic acid as well as 5(S),6(R)-epoxy-20-hydroxy- and 14(R),15(S)-epoxy-20-hydroxyeicosatrienoic acid.
AB - Aldehyde (1), derived from dimethyl L-malate, was exploited in a stereocontrolled total synthesis of the ω-hydroxylated eicosanoid metabolites 5(S),20- and 15(S),20-dihydroxyeicosatetraenoic acid as well as 5(S),6(R)-epoxy-20-hydroxy- and 14(R),15(S)-epoxy-20-hydroxyeicosatrienoic acid.
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U2 - 10.1039/C39870000389
DO - 10.1039/C39870000389
M3 - Article
AN - SCOPUS:0023151074
SN - 0022-4936
SP - 389
EP - 390
JO - Journal of the Chemical Society, Chemical Communications
JF - Journal of the Chemical Society, Chemical Communications
IS - 5
ER -