Aldehyde (1), derived from dimethyl L-malate, was exploited in a stereocontrolled total synthesis of the ω-hydroxylated eicosanoid metabolites 5(S),20- and 15(S),20-dihydroxyeicosatetraenoic acid as well as 5(S),6(R)-epoxy-20-hydroxy- and 14(R),15(S)-epoxy-20-hydroxyeicosatrienoic acid.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|State||Published - Dec 1 1987|
ASJC Scopus subject areas
- Molecular Medicine