Total synthesis of (+)-dihydromevinolin

J R Falck, Yang Yuh-Lin

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The potent hypocholesterolemic agent (+)-dihydromevinolin was synthesized from chiral pyranoside 5 and octahydronaphthalene 6 which was obtained from maleic anhydride Diels-Alder adduct 7 by intramolecular sulfoxide acylation and methyl cuprate addition.

Original languageEnglish (US)
Pages (from-to)3563-3566
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number33
DOIs
StatePublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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