Total synthesis of (+)-dihydromevinolin

J R Falck, Yang Yuh-Lin

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The potent hypocholesterolemic agent (+)-dihydromevinolin was synthesized from chiral pyranoside 5 and octahydronaphthalene 6 which was obtained from maleic anhydride Diels-Alder adduct 7 by intramolecular sulfoxide acylation and methyl cuprate addition.

Original languageEnglish (US)
Pages (from-to)3563-3566
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number33
DOIs
StatePublished - 1984

Fingerprint

sulfoxide
Maleic Anhydrides
Acylation
dihydromevinolin

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Total synthesis of (+)-dihydromevinolin. / Falck, J R; Yuh-Lin, Yang.

In: Tetrahedron Letters, Vol. 25, No. 33, 1984, p. 3563-3566.

Research output: Contribution to journalArticle

Falck, J R ; Yuh-Lin, Yang. / Total synthesis of (+)-dihydromevinolin. In: Tetrahedron Letters. 1984 ; Vol. 25, No. 33. pp. 3563-3566.
@article{a1aa76ff76fc4cecafa3e459f3236eda,
title = "Total synthesis of (+)-dihydromevinolin",
abstract = "The potent hypocholesterolemic agent (+)-dihydromevinolin was synthesized from chiral pyranoside 5 and octahydronaphthalene 6 which was obtained from maleic anhydride Diels-Alder adduct 7 by intramolecular sulfoxide acylation and methyl cuprate addition.",
author = "Falck, {J R} and Yang Yuh-Lin",
year = "1984",
doi = "10.1016/S0040-4039(01)91076-7",
language = "English (US)",
volume = "25",
pages = "3563--3566",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "33",

}

TY - JOUR

T1 - Total synthesis of (+)-dihydromevinolin

AU - Falck, J R

AU - Yuh-Lin, Yang

PY - 1984

Y1 - 1984

N2 - The potent hypocholesterolemic agent (+)-dihydromevinolin was synthesized from chiral pyranoside 5 and octahydronaphthalene 6 which was obtained from maleic anhydride Diels-Alder adduct 7 by intramolecular sulfoxide acylation and methyl cuprate addition.

AB - The potent hypocholesterolemic agent (+)-dihydromevinolin was synthesized from chiral pyranoside 5 and octahydronaphthalene 6 which was obtained from maleic anhydride Diels-Alder adduct 7 by intramolecular sulfoxide acylation and methyl cuprate addition.

UR - http://www.scopus.com/inward/record.url?scp=0021238939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021238939&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(01)91076-7

DO - 10.1016/S0040-4039(01)91076-7

M3 - Article

AN - SCOPUS:0021238939

VL - 25

SP - 3563

EP - 3566

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 33

ER -