Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review

N. R. Schneider; W. P. Bowman; E. P. Frenkel

Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review

N. R. Schneider, W. P. Bowman, E. P. Frenkel

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Abstract

The authors report two cases of secondary myelodysplasia and acute myeloid leukemia with t(3;21)(q26.3;q22) as the only cytogenetic abnormality in neoplastic bone marrow. This translocation was identified as a rare, recurring, non-random aberration in chronic myeloid leukemia less than five years ago and in secondary acute myeloid leukemia and myelodysplasia in 1990. The known and suspected cases in the literature are reviewed.

Original language	English (US)
Pages (from-to)	256-263
Number of pages	8
Journal	Annales de Genetique
Volume	34
Issue number	3-4
State	Published - 1991

Keywords

acute leukemia
chromosome
myelodysplasia
secondary
translocation

ASJC Scopus subject areas

Genetics

Cite this

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abstract = "The authors report two cases of secondary myelodysplasia and acute myeloid leukemia with t(3;21)(q26.3;q22) as the only cytogenetic abnormality in neoplastic bone marrow. This translocation was identified as a rare, recurring, non-random aberration in chronic myeloid leukemia less than five years ago and in secondary acute myeloid leukemia and myelodysplasia in 1990. The known and suspected cases in the literature are reviewed.",

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N2 - The authors report two cases of secondary myelodysplasia and acute myeloid leukemia with t(3;21)(q26.3;q22) as the only cytogenetic abnormality in neoplastic bone marrow. This translocation was identified as a rare, recurring, non-random aberration in chronic myeloid leukemia less than five years ago and in secondary acute myeloid leukemia and myelodysplasia in 1990. The known and suspected cases in the literature are reviewed.

AB - The authors report two cases of secondary myelodysplasia and acute myeloid leukemia with t(3;21)(q26.3;q22) as the only cytogenetic abnormality in neoplastic bone marrow. This translocation was identified as a rare, recurring, non-random aberration in chronic myeloid leukemia less than five years ago and in secondary acute myeloid leukemia and myelodysplasia in 1990. The known and suspected cases in the literature are reviewed.

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KW - chromosome

KW - myelodysplasia

KW - secondary

KW - translocation

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Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review

Abstract

Keywords

ASJC Scopus subject areas

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