Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review

N. R. Schneider, W. P. Bowman, E. P. Frenkel

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12 Scopus citations

Abstract

The authors report two cases of secondary myelodysplasia and acute myeloid leukemia with t(3;21)(q26.3;q22) as the only cytogenetic abnormality in neoplastic bone marrow. This translocation was identified as a rare, recurring, non-random aberration in chronic myeloid leukemia less than five years ago and in secondary acute myeloid leukemia and myelodysplasia in 1990. The known and suspected cases in the literature are reviewed.

Original languageEnglish (US)
Pages (from-to)256-263
Number of pages8
JournalAnnales de Genetique
Volume34
Issue number3-4
StatePublished - Dec 1 1991

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Keywords

  • acute leukemia
  • chromosome
  • myelodysplasia
  • secondary
  • translocation

ASJC Scopus subject areas

  • Genetics

Cite this

Schneider, N. R., Bowman, W. P., & Frenkel, E. P. (1991). Translocation (3;21)(q26;q22) in secondary leukemia. Report of two cases and literature review. Annales de Genetique, 34(3-4), 256-263.